ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTVGNSTNI FWQESPIGKT ERQKLLNQKG CVVWITGLSG SGKSTLACSL SRELNNRGKL 

        70         80         90        100        110        120 
SYILDGDNLR HGLNKDLGFK AEDRVENIRR VGEVAKLFAD AGLICIASLI SPYRKDRDAC 

       130        140        150        160        170        180 
REMIQNSSFI EVFMNMSLQL CEARDPKGLY KLARAGKIKG FTGIDDPYES PLNCEIELKE 

       190        200 
KEGECPSPVA MAEEVISYLE DKGFLQNE 

References and documentation are available.

Number of amino acids: 208

Molecular weight: 23146.46

Theoretical pI: 5.66

Amino acid composition: 
Ala (A)  12	  5.8%
Arg (R)  12	  5.8%
Asn (N)  12	  5.8%
Asp (D)  11	  5.3%
Cys (C)   7	  3.4%
Gln (Q)   6	  2.9%
Glu (E)  19	  9.1%
Gly (G)  18	  8.7%
His (H)   1	  0.5%
Ile (I)  14	  6.7%
Leu (L)  22	 10.6%
Lys (K)  16	  7.7%
Met (M)   5	  2.4%
Phe (F)   7	  3.4%
Pro (P)   7	  3.4%
Ser (S)  17	  8.2%
Thr (T)   6	  2.9%
Trp (W)   2	  1.0%
Tyr (Y)   5	  2.4%
Val (V)   9	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	      1010
Hydrogen    H	      1628
Nitrogen    N	       282
Oxygen      O	       315
Sulfur      S	        12

Formula: C1010H1628N282O315S12
Total number of atoms: 3247

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    18825
Abs 0.1% (=1 g/l)   0.813, assuming all pairs of Cys residues form cystines


Ext. coefficient    18450
Abs 0.1% (=1 g/l)   0.797, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.19
This classifies the protein as unstable.



Aliphatic index: 85.82

Grand average of hydropathicity (GRAVY): -0.382