ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTYQAATIV AAPNEFRVPF PPFVQISKVQ FQREAGSRLL AASGWDGTCR VYEVGKLGDI 

        70         80         90        100        110        120 
SEKLVFTHGK PLLTCTFAGY NKVAFGGVDH NVKLADIETG NGTQLGSHAL AVRCMEFNPM 

       130        140        150        160        170        180 
SSLIVSGGWD SSVKLWDARS YGNGAIESVN VSSSVYAMDV LKHTILVGTK DRKIFMYDSR 

       190        200        210        220        230        240 
KLREPLQVRD SPLKYQTRAV QFFPTGEAFV VSSIEGRVAV EYVDQSGEEM MKRKYAFKCH 

       250        260        270        280        290        300 
REKDTDGTEL IHPVHTVAFH PKYGTFATGG ADGIVNIWDP FNRKRIIQLH KFETSISSLS 

       310        320        330        340 
FNEDGSQLAI ATSYQYEKEI DPSPLPNNSI TIRHITDPES RPK 

References and documentation are available.

Number of amino acids: 343

Molecular weight: 38127.25

Theoretical pI: 7.71

Amino acid composition: 
Ala (A)  24	  7.0%
Arg (R)  18	  5.2%
Asn (N)  12	  3.5%
Asp (D)  18	  5.2%
Cys (C)   4	  1.2%
Gln (Q)  12	  3.5%
Glu (E)  20	  5.8%
Gly (G)  26	  7.6%
His (H)  10	  2.9%
Ile (I)  20	  5.8%
Leu (L)  21	  6.1%
Lys (K)  21	  6.1%
Met (M)   7	  2.0%
Phe (F)  18	  5.2%
Pro (P)  17	  5.0%
Ser (S)  30	  8.7%
Thr (T)  21	  6.1%
Trp (W)   4	  1.2%
Tyr (Y)  12	  3.5%
Val (V)  28	  8.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1704
Hydrogen    H	      2648
Nitrogen    N	       466
Oxygen      O	       507
Sulfur      S	        11

Formula: C1704H2648N466O507S11
Total number of atoms: 5336

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    40130
Abs 0.1% (=1 g/l)   1.053, assuming all pairs of Cys residues form cystines


Ext. coefficient    39880
Abs 0.1% (=1 g/l)   1.046, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.66
This classifies the protein as unstable.



Aliphatic index: 77.29

Grand average of hydropathicity (GRAVY): -0.301