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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSVPKKRNHG KLPPSTKDVD DPSLKYTKAA PKCEQVAEHW LLQPLPEPES RYSFWVTIVT

70 80 90 100 110 120
LLAFAARFYK IWYPKEVVFD EVHFGKFASY YLERSYFFDV HPPFAKMMIA FIGWLCGYDG

130 140 150 160 170 180
SFKFDEIGYS YETHPAPYIA YRSFNAILGT LTVPIMFNTL KELNFRAITC AFASLLVAID

190 200 210 220 230 240
TAHVTETRLI LLDAILIISI AATMYCYVRF YKCQLRQPFT WSWYIWLHAT GLSLSFVIST

250 260 270 280 290 300
KYVGVMTYSA IGFAAVVNLW QLLDIKAGLS LRQFMRHFSK RLNGLVLIPF VIYLFWFWVH

310 320 330 340 350 360
FTVLNTSGPG DAFMSAEFQE TLKDSPLSVD SKTVNYFDII TIKHQDTDAF LHSHLARYPQ

370 380 390 400 410 420
RYEDGRISSA GQQVTGYTHP DFNNQWEVLP PHGSDVGKGQ AVLLNQHIRL RHVATDTYLL

430 440 450 460 470 480
AHDVASPFYP TNEEITTVTL EEGDGELYPE TLFAFQPLKK SDEGHVLKSK TVSFRLFHVD

490 500 510 520 530 540
TSVALWTHND ELLPDWGFQQ QEINGNKKVI DPSNNWVVDE IVNLDEVRKV YIPKVVKPLP

550 560 570 580 590 600
FLKKWIETQK SMFEHNNKLS SEHPFASEPY SWPGSLSGVS FWTNGDEKKQ IYFIGNIIGW

610 620 630 640 650 660
WFQVISLAVF VGIIVADLIT RHRGYYALNK MTREKLYGPL MFFFVSWCCH YFPFFLMARQ

670 680 690 700 710 720
KFLHHYLPAH LIACLFSGAL WEVIFSDCKS LDLEKDEDIS GASYERNPKV YVKPYTVFLV

730 740 750 760
CVSCAVAWFF VYFSPLVYGD VSLSPSEVVS REWFDIELNF SK


References and documentation are available.

Number of amino acids: 762 Molecular weight: 87966.29 Theoretical pI: 6.46
Amino acid composition: 
Ala (A) 47 6.2% Arg (R) 25 3.3% Asn (N) 25 3.3% Asp (D) 37 4.9% Cys (C) 11 1.4% Gln (Q) 22 2.9% Glu (E) 39 5.1% Gly (G) 36 4.7% His (H) 27 3.5% Ile (I) 44 5.8% Leu (L) 74 9.7% Lys (K) 44 5.8% Met (M) 12 1.6% Phe (F) 59 7.7% Pro (P) 41 5.4% Ser (S) 56 7.3% Thr (T) 40 5.2% Trp (W) 23 3.0% Tyr (Y) 39 5.1% Val (V) 61 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 76 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 4116 Hydrogen H 6115 Nitrogen N 1005 Oxygen O 1097 Sulfur S 23 Formula: C4116H6115N1005O1097S23 Total number of atoms: 12356 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 185235 Abs 0.1% (=1 g/l) 2.106, assuming all pairs of Cys residues form cystines Ext. coefficient 184610 Abs 0.1% (=1 g/l) 2.099, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.01 This classifies the protein as stable. Aliphatic index: 89.78 Grand average of hydropathicity (GRAVY): 0.014