ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSVPSSLSQS AINANSHGGP ALSFPFPLHA AHNQLLNAKL QATAVVPKDL RSAMGEGSVP 

        70         80         90        100        110        120 
EPGPANAKWL KEGQNQLRRA ATAHRDQNRN VTLTLAEEAS QEAETAPLGP KGLMHLYSEL 

       130        140        150        160        170        180 
ELSAHNAANR GLHGSALIIN TQGLGPDEGE EKAAGEVEEE DEDEEEEDEE EEDLSSPQGL 

       190        200        210        220        230        240 
PEPLENVEVP SGPQVLTDGP REHSKSASLL FGMRNSAASD EDSSWATLSQ GSPSYGSPED 

       250        260        270        280        290        300 
TDSFWNPNAF ETDSDLPAGW MRVQDTSGTY YWHIPTGTTQ WEPPGRASPS QGNSPQEESQ 

       310        320        330        340        350        360 
LTWTGFAHQE GFEEGEFWKD EPSEEAPMEL GLKDPEEGTL PFSAQSLSPE PVPQEEENLP 

       370        380        390        400        410        420 
QRNANPGIKC FAVRSLGWVE MTEEELAPGR SSVAVNNCIR QLSYHKNNLH DPMSGGWGEG 

       430        440        450        460        470        480 
KDLLLQLEDE TLKLVEPQNQ TLLHAQPIVS IRVWGVGRDS GRERDFAYVA RDKLTQMLKC 

       490        500        510        520        530        540 
HVFRCEAPAK NIATSLHEIC SKIMSERRNA RCLVNGLSLD HSKLVDVPFQ VEFPAPKNEL 

       550        560        570        580        590        600 
VQKFQVYYLG NVPVAKPVGV DVINGALESV LSSSSREQWT PSHVSVAPAT LTILHQQTEA 

       610        620        630        640        650        660 
VLGECRVRFL SFLAVGRDVH TFAFIMAAGP ASFCCHMFWC EPNAASLSEA VQAACMLRYQ 

       670        680        690        700        710 
KCLDARSQTS TSCLPAPPAE SVARRVGWTV RRGVQSLWGS LKPKRLGSQT P 

References and documentation are available.

Number of amino acids: 711

Molecular weight: 77656.47

Theoretical pI: 4.91

Amino acid composition: 
Ala (A)  65	  9.1%
Arg (R)  34	  4.8%
Asn (N)  31	  4.4%
Asp (D)  28	  3.9%
Cys (C)  13	  1.8%
Gln (Q)  37	  5.2%
Glu (E)  70	  9.8%
Gly (G)  51	  7.2%
His (H)  20	  2.8%
Ile (I)  14	  2.0%
Leu (L)  68	  9.6%
Lys (K)  24	  3.4%
Met (M)  13	  1.8%
Phe (F)  21	  3.0%
Pro (P)  54	  7.6%
Ser (S)  68	  9.6%
Thr (T)  32	  4.5%
Trp (W)  15	  2.1%
Tyr (Y)   9	  1.3%
Val (V)  44	  6.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 98
Total number of positively charged residues (Arg + Lys): 58

Atomic composition:

Carbon      C	      3389
Hydrogen    H	      5270
Nitrogen    N	       960
Oxygen      O	      1085
Sulfur      S	        26

Formula: C3389H5270N960O1085S26
Total number of atoms: 10730

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    96660
Abs 0.1% (=1 g/l)   1.245, assuming all pairs of Cys residues form cystines


Ext. coefficient    95910
Abs 0.1% (=1 g/l)   1.235, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 62.90
This classifies the protein as unstable.



Aliphatic index: 72.07

Grand average of hydropathicity (GRAVY): -0.508