ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSVQIFGDQV TEERAENARL SAFVGAIAVG DLVKSTLGPK GMDKLLQSAS SNTCMVTNDG 

        70         80         90        100        110        120 
ATILKSIPLD NPAAKVLVNI SKVQDDEVGD GTTSVTVLSA ELLREAEKLI DQSKIHPQTI 

       130        140        150        160        170        180 
IEGYRLASAA ALDALTKAAV DNSHDKTMFR EDLIHIAKTT LSSKILSQDK DHFAELATNA 

       190        200        210        220        230        240 
ILRLKGSTNL EHIQIIKILG GKLSDSFLDE GFILAKKFGN NQPKRIENAK ILIANTTLDT 

       250        260        270        280        290        300 
DKVKIFGTKF KVDSTAKLAQ LEKAEREKMK NKIAKISKFG INTFINRQLI YDYPEQLFTD 

       310        320        330        340        350        360 
LGINSIEHAD FEGVERLALV TGGEVVSTFD EPSKCKLGEC DVIEEIMLGE QPFLKFSGCK 

       370        380        390        400        410        420 
AGEACTIVLR GATDQTLDEA ERSLHDALSV LSQTTKETRT VLGGGCAEMV MSKAVDTEAQ 

       430        440        450        460        470        480 
NIDGKKSLAV EAFARALRQL PTILADNAGF DSSELVSKLR SSIYNGISTS GLDLNNGTIA 

       490        500        510        520 
DMRQLGIVES YKLKRAVVSS ASEAAEVLLR VDNIIRARPR TANRQHM 

References and documentation are available.

Number of amino acids: 527

Molecular weight: 57203.40

Theoretical pI: 5.79

Amino acid composition: 
Ala (A)  52	  9.9%
Arg (R)  23	  4.4%
Asn (N)  23	  4.4%
Asp (D)  35	  6.6%
Cys (C)   6	  1.1%
Gln (Q)  19	  3.6%
Glu (E)  37	  7.0%
Gly (G)  34	  6.5%
His (H)   8	  1.5%
Ile (I)  40	  7.6%
Leu (L)  56	 10.6%
Lys (K)  42	  8.0%
Met (M)  10	  1.9%
Phe (F)  18	  3.4%
Pro (P)  10	  1.9%
Ser (S)  41	  7.8%
Thr (T)  36	  6.8%
Trp (W)   0	  0.0%
Tyr (Y)   5	  0.9%
Val (V)  32	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 72
Total number of positively charged residues (Arg + Lys): 65

Atomic composition:

Carbon      C	      2502
Hydrogen    H	      4122
Nitrogen    N	       696
Oxygen      O	       796
Sulfur      S	        16

Formula: C2502H4122N696O796S16
Total number of atoms: 8132

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     7825
Abs 0.1% (=1 g/l)   0.137, assuming all pairs of Cys residues form cystines


Ext. coefficient     7450
Abs 0.1% (=1 g/l)   0.130, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.00
This classifies the protein as stable.



Aliphatic index: 98.52

Grand average of hydropathicity (GRAVY): -0.153