ProtParam
User-provided sequence:
10 20 30 40 50 60
MSVSLEQTLG FRIKVTNVLD VVTEGRLYSF NSSNNTLTIQ TTKKNQSPQN FKVIKCTFIK
70 80 90 100 110 120
HLEVIGDKPS FNSFKKQQIK PSYVNVERVE KLLKESVIAS KKKELLRGKG VSAEGQFIFD
130 140 150 160 170 180
QIFKTIGDTK WVAKDIIILD DVKVQPPYKV EDIKVLHEGS NQSITLIQRI VERSWEQLEQ
DDGRKGG
References and
documentation are available.
Number of amino acids: 187
Molecular weight: 21313.56
Theoretical pI: 9.41
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 30
Atomic composition:
Carbon C 957
Hydrogen H 1555
Nitrogen N 259
Oxygen O 285
Sulfur S 2
Formula: C
957H
1555N
259O
285S
2
Total number of atoms: 3058
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 0.726, assuming all pairs of Cys residues form cystines
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 0.726, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 26.18
This classifies the protein as stable.
Aliphatic index: 94.17
Grand average of hydropathicity (GRAVY): -0.442