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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSVTGTEIDS DTAKNILSVD ELQNYGINAS DLQKLKSGGI YTVNTVLSTT RRHLCKIKGL

70 80 90 100 110 120
SEVKVEKIKE AAGKIIQVGF IPATVQLDIR QRVYSLSTGS KQLDSILGGG IMTMSITEVF

130 140 150 160 170 180
GEFRCGKTQM SHTLCVTTQL PREMGGGEGK VAYIDTEGTF RPERIKQIAE GYELDPESCL

190 200 210 220 230 240
ANVSYARALN SEHQMELVEQ LGEELSSGDY RLIVVDSIMA NFRVDYCGRG ELSERQQKLN

250 260 270 280 290 300
QHLFKLNRLA EEFNVAVFLT NQVQSDPGAS ALFASADGRK PIGGHVLAHA SATRILLRKG

310 320 330
RGDERVAKLQ DSPDMPEKEC VYVIGEKGIT DSSD


References and documentation are available.

Number of amino acids: 334 Molecular weight: 36612.57 Theoretical pI: 5.66
Amino acid composition: 
Ala (A) 21 6.3% Arg (R) 19 5.7% Asn (N) 11 3.3% Asp (D) 18 5.4% Cys (C) 6 1.8% Gln (Q) 17 5.1% Glu (E) 27 8.1% Gly (G) 31 9.3% His (H) 6 1.8% Ile (I) 22 6.6% Leu (L) 31 9.3% Lys (K) 20 6.0% Met (M) 8 2.4% Phe (F) 9 2.7% Pro (P) 8 2.4% Ser (S) 27 8.1% Thr (T) 20 6.0% Trp (W) 0 0.0% Tyr (Y) 9 2.7% Val (V) 24 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 45 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1590 Hydrogen H 2585 Nitrogen N 451 Oxygen O 509 Sulfur S 14 Formula: C1590H2585N451O509S14 Total number of atoms: 5149 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 13785 Abs 0.1% (=1 g/l) 0.377, assuming all pairs of Cys residues form cystines Ext. coefficient 13410 Abs 0.1% (=1 g/l) 0.366, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.16 This classifies the protein as stable. Aliphatic index: 89.01 Grand average of hydropathicity (GRAVY): -0.299