ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSVWTTANNS GLETPTKSPI TSSVPRAARS SAVITTGNHQ QHHFQHVVAA AVAAATSVAT 

        70         80         90        100        110        120 
GHQFQQQFPL HAHPHPQHHS NSPTGSGSNS NNSAGFQRTS ISNSLLQFPP PPPPSSQNQA 

       130        140        150        160        170        180 
KPRGHHRTAS SSMSQSGEDL HSPTYLSWRK LQLSRAKLKA SSKTSALLSG FAMVAMVEVQ 

       190        200        210        220        230        240 
LDHDTNVPPG MLIAFAICTT LLVAVHMLAL MISTCILPNI ETVCNLHSIS LVHESPHERL 

       250        260        270        280        290        300 
HWYIETAWAF STLLGLILFL LEIAILCWVK FYDLSPPAAW SACVVLIPVM IIFMAFAIHF 

       310        320        330        340        350 
YRSLVSHKYE VTVSGIRELE MLKEQMEQDH LEHHNNIRNN GMNYGASGDI V 

References and documentation are available.

Number of amino acids: 351

Molecular weight: 38507.00

Theoretical pI: 7.41

Amino acid composition: 
Ala (A)  33	  9.4%
Arg (R)  11	  3.1%
Asn (N)  17	  4.8%
Asp (D)   6	  1.7%
Cys (C)   5	  1.4%
Gln (Q)  17	  4.8%
Glu (E)  14	  4.0%
Gly (G)  15	  4.3%
His (H)  24	  6.8%
Ile (I)  20	  5.7%
Leu (L)  34	  9.7%
Lys (K)   9	  2.6%
Met (M)  12	  3.4%
Phe (F)  13	  3.7%
Pro (P)  22	  6.3%
Ser (S)  42	 12.0%
Thr (T)  22	  6.3%
Trp (W)   6	  1.7%
Tyr (Y)   6	  1.7%
Val (V)  23	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 20

Atomic composition:

Carbon      C	      1715
Hydrogen    H	      2669
Nitrogen    N	       481
Oxygen      O	       496
Sulfur      S	        17

Formula: C1715H2669N481O496S17
Total number of atoms: 5378

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    42190
Abs 0.1% (=1 g/l)   1.096, assuming all pairs of Cys residues form cystines


Ext. coefficient    41940
Abs 0.1% (=1 g/l)   1.089, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.59
This classifies the protein as unstable.



Aliphatic index: 88.40

Grand average of hydropathicity (GRAVY): -0.020