ProtParam
User-provided sequence:
10 20 30 40 50 60
MSYLLPHLHS GWAVDQAILA EEERLVIIRF GHDWDETCMQ MDEVLAAVAE TIKNFAVIYL
70 80 90 100 110 120
VDITEVPDFN TMYELYDPST VMFFFRNKHI MIDLGTGNNN KINWALKDKQ EFIDIVETVY
130 140
RGARKGRGLV IAPKDYSTKY RY
References and
documentation are available.
Number of amino acids: 142
Molecular weight: 16559.01
Theoretical pI: 5.14
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 15
Atomic composition:
Carbon C 753
Hydrogen H 1152
Nitrogen N 192
Oxygen O 215
Sulfur S 7
Formula: C
753H
1152N
192O
215S
7
Total number of atoms: 2319
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 28420
Abs 0.1% (=1 g/l) 1.716, assuming all pairs of Cys residues form cystines
Ext. coefficient 28420
Abs 0.1% (=1 g/l) 1.716, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 23.21
This classifies the protein as stable.
Aliphatic index: 92.68
Grand average of hydropathicity (GRAVY): -0.152