ProtParam
User-provided sequence:
10 20 30 40 50 60
MSYTCNSGNY SSQSFGGFLR QPVSTYNSFY PTSNVVYSPK NFQLGSSFYN GQQETFSEPL
70 80 90 100 110 120
EGHLPCVGSA SFHTSCFRPK QYFSSPCQGG FTGSFGYGNT GFGAFGFGSS GIRSQGCGSN
130 140 150
FYRPGYFSSK SIQSSYYQPG YSSGFCGSNF
References and
documentation are available.
Number of amino acids: 150
Molecular weight: 16241.62
Theoretical pI: 8.75
Total number of negatively charged residues (Asp + Glu): 3
Total number of positively charged residues (Arg + Lys): 7
Atomic composition:
Carbon C 728
Hydrogen H 1016
Nitrogen N 188
Oxygen O 226
Sulfur S 7
Formula: C
728H
1016N
188O
226S
7
Total number of atoms: 2165
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 19745
Abs 0.1% (=1 g/l) 1.216, assuming all pairs of Cys residues form cystines
Ext. coefficient 19370
Abs 0.1% (=1 g/l) 1.193, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 52.85
This classifies the protein as unstable.
Aliphatic index: 24.67
Grand average of hydropathicity (GRAVY): -0.471