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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTAEDILLRE RTSTTTQRPV NSEQYLNVQL ATAPVKNFQT TSEISRQTLV DTSNDDVYSI

70 80 90 100 110 120
KNLKGSRNPI SPSVSNVGFQ SIFHTVDHPR SKVSVASNHS LRSNDNASAA TSKSGSSQIG

130 140 150 160 170 180
ESHSVDTVEC SNNLSKKLSS DAISITQKSL HSTPSGRYMK GKASGFFNRR NRAHTTISSD

190 200 210 220 230 240
PASFLTDSST LHNSSHSFRN VIKNFFQNKS HRHIGQDAIE PAIPNSLSKF LHSSYGRHKS

250 260 270 280 290 300
PSQFIHTNAG QLVDSGTSVY SLNVNPSGVN PNTIVEDPLS GTDPASPNPV SMLHDLLRNL

310 320 330 340 350 360
PSLEANYKHF NSQELTTLTN NIWNIFCSNV AELFRTQRIW KLRAKIENFN EVLEFYCILK

370 380 390 400 410 420
TDPRVTHSGM NRIISDLKEF LVSSLYNLEN QIVFNYSNED TINNALKRLG VIWRIFYQEV

430 440 450 460 470 480
YYDLAAVLLP LDQSIREDGN STVLKSGNES RTHINGNYSI GFLLLMCFRD SIVLPCYENF

490 500 510 520 530 540
VNSNDGISKS FQLYIFNQEE ESNVTETDKL TLLQCFGILS TIQSNDRNQR IIEELLAGIR


MSI


References and documentation are available.

Number of amino acids: 543 Molecular weight: 60840.95 Theoretical pI: 7.00
Amino acid composition: 
Ala (A) 22 4.1% Arg (R) 28 5.2% Asn (N) 52 9.6% Asp (D) 25 4.6% Cys (C) 6 1.1% Gln (Q) 22 4.1% Glu (E) 27 5.0% Gly (G) 22 4.1% His (H) 17 3.1% Ile (I) 38 7.0% Leu (L) 50 9.2% Lys (K) 23 4.2% Met (M) 6 1.1% Phe (F) 25 4.6% Pro (P) 20 3.7% Ser (S) 75 13.8% Thr (T) 36 6.6% Trp (W) 3 0.6% Tyr (Y) 15 2.8% Val (V) 31 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 52 Total number of positively charged residues (Arg + Lys): 51 Atomic composition: Carbon C 2664 Hydrogen H 4199 Nitrogen N 761 Oxygen O 848 Sulfur S 12 Formula: C2664H4199N761O848S12 Total number of atoms: 8484 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39225 Abs 0.1% (=1 g/l) 0.645, assuming all pairs of Cys residues form cystines Ext. coefficient 38850 Abs 0.1% (=1 g/l) 0.639, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.59 This classifies the protein as unstable. Aliphatic index: 83.81 Grand average of hydropathicity (GRAVY): -0.427