ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTASDLLTLP QLLAQYSSSA PQNKVFYTTS TKNSHSSFKG LESVATDATH LLNNQDPLNT 

        70         80         90        100        110        120 
IKDQLSKDIL TTVFTDETTL VKSIHHLYSL PNKLPLVITV DLNLQDYSAI PALKDLSFPI 

       130        140        150        160        170        180 
LISSDLQTAI SNADSSYKIA TSSLTPVFHF LNLEKIGTST AIEQDIDFPT LEIANEETKV 

       190        200        210        220        230        240 
ALSEATDSLT NFELVKGKES ITTVIVNLSP YDAEFSSVLP SNVGLIKIRV YRPWNFSKFL 

       250        260        270        280        290        300 
EILPSSVTKI AVLQGVSKKS QSNEFQPFLL DFFGNFNELV SRNIEQVVLT NIGNVNDYGN 

       310        320        330        340        350        360 
VINTVISNIN KKEPDNNLFL GESNEKAEEQ AEVTQLISSV KKVVNLEDAY IKVLKQLFSS 

       370        380        390        400        410        420 
NLQILNQFSS ETIEPSNPEF GFGRFLKQEA QREELISLAK TSLDPSLYLS EDANKIVQLL 

       430        440        450        460        470        480 
SKWLSFNGRD LDEAQLQEAN ATGLEIFQLL QSNQDSSTVL KFLKIAPTSD SFIFKSSWLI 

       490        500        510        520        530        540 
GSDAWSYDLG HSGIQQVLSS RKNINVLLID SEPYDHRKQN QDRKKDVGLY AMNYYSAYVA 

       550        560        570        580        590        600 
SVAVYASYTQ LLTAIIEASK YNGPSIVLAY LPYNSENDTP LEVLKETKNA VESGYWPLYR 

       610        620        630        640        650        660 
FNPVYDDPST DKEAFSLDSS VIRKQLQDFL DRENKLTLLT RKDPSLSRNL KQSAGDALTR 

       670        680        690        700        710        720 
KQEKRSKAAF DQLLEGLSGP PLHVYYASDG GNAANLAKRL AARASARGLK ATVLSMDDII 

       730        740        750        760        770        780 
LEELPGEENV VFITSTAGQG EFPQDGKSFW EALKNDTDLD LASLNVAVFG LGDSEYWPRK 

       790        800        810        820        830        840 
EDKHYFNKPS QDLFKRLELL SAKALIPLGL GDDQDADGFQ TAYSEWEPKL WEALGVSGAA 

       850        860        870        880        890        900 
VDDEPKPVTN EDIKRESNFL RGTISENLKD TSSGGVTHAN EQLMKFHGIY TQDDRDIREI 

       910        920        930        940        950        960 
RKSQGLEPYY MFMARARLPG GKTTPQQWLA LDHLSDTSGN GTLKLTTRAT FQIHGVLKKN 

       970        980        990       1000       1010       1020 
LKHTLRGMNA VLMDTLAAAG DVNRNVMVSA LPTNAKVHQQ IADMGKLISD HFLPKTTAYH 

      1030       1040       1050       1060       1070       1080 
EVWLEGPEEQ DDDPSWPSIF ENRKDGPRKK KTLVSGNALV DIEPIYGPTY LPRKFKFNIA 

      1090       1100       1110       1120       1130       1140 
VPPYNDVDVL SIDVGLVAIV NPETQIVEGY NVFVGGGMGT THNNKKTYPR LGSCLGFVKT 

      1150       1160       1170       1180       1190       1200 
EDIIPPLEGI VIVQRDHGDR KDRKHARLKY TVDDMGVEGF KQKVEEYWGK KFEPERPFEF 

      1210       1220       1230       1240       1250       1260 
KSNIDYFGWI KDETGLNHFT AFIENGRVED TPDLPQKTGI RKVAEYMLKT NSGHFRLTGN 

      1270       1280       1290       1300       1310       1320 
QHLVISNITD EHVAGIKSIL KTYKLDNTDF SGLRLSSSSC VGLPTCGLAF AESERFLPDI 

      1330       1340       1350       1360       1370       1380 
ITQLEDCLEE YGLRHDSIIM RMTGCPNGCS RPWLGELALV GKAPHTYNLM LGGGYLGQRL 

      1390       1400       1410       1420       1430       1440 
NKLYKANVKD EEIVDYIKPL FKRYALEREE GEHFGDFCIR VGIIKPTTEG KYFHEDVSED 


AY 

References and documentation are available.

Number of amino acids: 1442

Molecular weight: 161219.09

Theoretical pI: 5.31

Amino acid composition: 
Ala (A)  88	  6.1%
Arg (R)  52	  3.6%
Asn (N)  82	  5.7%
Asp (D)  97	  6.7%
Cys (C)   7	  0.5%
Gln (Q)  56	  3.9%
Glu (E)  97	  6.7%
Gly (G)  89	  6.2%
His (H)  28	  1.9%
Ile (I)  81	  5.6%
Leu (L) 162	 11.2%
Lys (K) 102	  7.1%
Met (M)  16	  1.1%
Phe (F)  63	  4.4%
Pro (P)  66	  4.6%
Ser (S) 118	  8.2%
Thr (T)  87	  6.0%
Trp (W)  15	  1.0%
Tyr (Y)  51	  3.5%
Val (V)  85	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 194
Total number of positively charged residues (Arg + Lys): 154

Atomic composition:

Carbon      C	      7222
Hydrogen    H	     11311
Nitrogen    N	      1909
Oxygen      O	      2225
Sulfur      S	        23

Formula: C7222H11311N1909O2225S23
Total number of atoms: 22690

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   158865
Abs 0.1% (=1 g/l)   0.985, assuming all pairs of Cys residues form cystines


Ext. coefficient   158490
Abs 0.1% (=1 g/l)   0.983, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.74
This classifies the protein as stable.



Aliphatic index: 88.92

Grand average of hydropathicity (GRAVY): -0.374