ProtParam
User-provided sequence:
10 20 30 40 50 60
MTCGLVRIRL ARFGRKNSPV YNIVVANSRK ARDAKPIEVL GTYVPVPSPV TKRELKRGVV
70 80 90 100 110 120
PIKDVKLDFD RTKYWIGVGA QPSETVTKLL RKAGILNDAW ATSKNSNVNR KVVFERMETL
E
References and
documentation are available.
Number of amino acids: 121
Molecular weight: 13638.99
Theoretical pI: 10.40
Total number of negatively charged residues (Asp + Glu): 11
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 609
Hydrogen H 1009
Nitrogen N 179
Oxygen O 169
Sulfur S 3
Formula: C
609H
1009N
179O
169S
3
Total number of atoms: 1969
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 1.134, assuming all pairs of Cys residues form cystines
Ext. coefficient 15470
Abs 0.1% (=1 g/l) 1.134, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 37.35
This classifies the protein as stable.
Aliphatic index: 93.31
Grand average of hydropathicity (GRAVY): -0.330