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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTDFDLMNFP FHERLDSPVS ENGEIKDGEP IPQNWLNENH VGKSILPLFV NPEDVINCNF

70 80 90 100 110 120
SNARDSYEEN KSPSMDQMNY ARNTSYQESP GLQERPKNEK DKSPIGTDVH KKDVPNFIHS

130 140 150 160 170 180
TPRENSSKHF TRANEQASAQ PTDEHTSPDI SIEDCNGAKI FLQNSLSKED FRMLENVILG

190 200 210 220 230 240
YQKKVIELGR DNLRQEERAN SLQKELEAAT KSNDKTLDNK KKIEEQTVLI ENLTKDLSLN

250 260 270 280 290 300
KEMLEKANDT IQTKHTALLS LTDSLRKAEL FEIPIGILFF DLYDSEENSS KLDHILQEKY

310 320 330 340 350 360
PNIKGFLCAS QQEELSRISQ RFKNAKAEAE DLRNELENKK IEIQTMREKN NTLIGTNKTL

370 380 390 400 410 420
SKQNKILCDK FDKLTIDEKE ILKGCNEEIK IKLERLNERL GSWEKSKEKY ETSLKDKEKM

430 440 450 460 470 480
LADAEKKTNT LSKELDNLRS RFGNLEGNTS ERITIKNILQ SRPDISAEEC NFLMVEQIDS

490 500 510 520 530 540
ANLTTLQNTV KEIVLAVGIP YPKLRRKIPL LAIKLKYENI MLSNFAQRLH RQVYSQEMNL

550 560 570 580
KKFTDQAYYD FMSTRRMDSI DHHLERCLDH LYDHILEKMV K


References and documentation are available.

Number of amino acids: 581 Molecular weight: 67400.22 Theoretical pI: 5.74
Amino acid composition: 
Ala (A) 24 4.1% Arg (R) 28 4.8% Asn (N) 48 8.3% Asp (D) 38 6.5% Cys (C) 7 1.2% Gln (Q) 25 4.3% Glu (E) 62 10.7% Gly (G) 16 2.8% His (H) 13 2.2% Ile (I) 40 6.9% Leu (L) 63 10.8% Lys (K) 60 10.3% Met (M) 14 2.4% Phe (F) 20 3.4% Pro (P) 20 3.4% Ser (S) 43 7.4% Thr (T) 30 5.2% Trp (W) 2 0.3% Tyr (Y) 13 2.2% Val (V) 15 2.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 100 Total number of positively charged residues (Arg + Lys): 88 Atomic composition: Carbon C 2941 Hydrogen H 4740 Nitrogen N 826 Oxygen O 941 Sulfur S 21 Formula: C2941H4740N826O941S21 Total number of atoms: 9469 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30745 Abs 0.1% (=1 g/l) 0.456, assuming all pairs of Cys residues form cystines Ext. coefficient 30370 Abs 0.1% (=1 g/l) 0.451, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.21 This classifies the protein as unstable. Aliphatic index: 80.76 Grand average of hydropathicity (GRAVY): -0.850