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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTDRNFSPQQ GQGPQESLPE GPQPSTMIQR EEMNMPRQYS EQQQLQENEG EGENTRLPVS

70 80 90 100 110 120
EEEFRMVQEL QAIQAGHDQA NLPPSGRGSL EGEDNGNSDG ADGEMDEDDE EYDVFRNVGQ

130 140 150 160 170 180
GLVGHYKEIM IRYWQELINE IESTNEPGSE HQDDFKSHSL PFARIRKVMK TDEDVKMISA

190 200 210 220 230 240
EAPIIFAKAC EIFITELTMR AWCVAERNKR RTLQKADIAE ALQKSDMFDF LIDVVPRRPL


PQ


References and documentation are available.

Number of amino acids: 242 Molecular weight: 27675.64 Theoretical pI: 4.50
Amino acid composition: 
Ala (A) 14 5.8% Arg (R) 16 6.6% Asn (N) 11 4.5% Asp (D) 17 7.0% Cys (C) 2 0.8% Gln (Q) 21 8.7% Glu (E) 31 12.8% Gly (G) 16 6.6% His (H) 4 1.7% Ile (I) 14 5.8% Leu (L) 14 5.8% Lys (K) 9 3.7% Met (M) 11 4.5% Phe (F) 9 3.7% Pro (P) 15 6.2% Ser (S) 14 5.8% Thr (T) 8 3.3% Trp (W) 2 0.8% Tyr (Y) 4 1.7% Val (V) 10 4.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 48 Total number of positively charged residues (Arg + Lys): 25 Atomic composition: Carbon C 1187 Hydrogen H 1859 Nitrogen N 341 Oxygen O 397 Sulfur S 13 Formula: C1187H1859N341O397S13 Total number of atoms: 3797 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17085 Abs 0.1% (=1 g/l) 0.617, assuming all pairs of Cys residues form cystines Ext. coefficient 16960 Abs 0.1% (=1 g/l) 0.613, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 63.92 This classifies the protein as unstable. Aliphatic index: 62.89 Grand average of hydropathicity (GRAVY): -0.907