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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTEDKSQVKI RFFTREKDEL LHVQDTPMYA PISLKRYGLS EIVNHLLGSE KPVPFDFLIE

70 80 90 100 110 120
GELLRTSLHD YLTKKGLSSE ASLNVEYTRA ILPPSYLNSF SNEDWVSSLD VGDGSKHIIS

130 140 150 160 170 180
GSYDGIVRTW DLSGNVQKQY SGHSGPIRAV KYISNTRLVS AGNDRTLRLW KTKNDDLKLT

190 200 210 220 230 240
SQQQAQEDDD DEVNIEDGKT LAILEGHKAP VVSIDVSDNS RILSASYDNS IGFWSTIYKE

250 260 270 280 290 300
MTVVDPLEDI NNPNNKISTA ARKRRKLTMK DGTIRRRAPL SLLESHTAPV EQVIFDSTDN

310 320 330 340 350 360
TVGYSVSQDH TIKTWDLVTA RCIDTRTTSY SLLSIAQLST LNLLACGSSA RHITLHDPRV

370 380 390 400 410 420
GASSKVTQQQ LIGHKNFVSS LDTCPENEYI LCSGSHDGTV KVWDVRSTSP MYTITREDKS

430 440 450 460
VQKGVNDKVF AVKWAEKVGI ISAGQDKKIQ INKGDNIFKN


References and documentation are available.

Number of amino acids: 460 Molecular weight: 51358.76 Theoretical pI: 6.47
Amino acid composition: 
Ala (A) 21 4.6% Arg (R) 23 5.0% Asn (N) 23 5.0% Asp (D) 37 8.0% Cys (C) 4 0.9% Gln (Q) 17 3.7% Glu (E) 22 4.8% Gly (G) 26 5.7% His (H) 12 2.6% Ile (I) 32 7.0% Leu (L) 41 8.9% Lys (K) 33 7.2% Met (M) 5 1.1% Phe (F) 10 2.2% Pro (P) 15 3.3% Ser (S) 51 11.1% Thr (T) 34 7.4% Trp (W) 7 1.5% Tyr (Y) 14 3.0% Val (V) 33 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2255 Hydrogen H 3603 Nitrogen N 633 Oxygen O 718 Sulfur S 9 Formula: C2255H3603N633O718S9 Total number of atoms: 7218 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 59610 Abs 0.1% (=1 g/l) 1.161, assuming all pairs of Cys residues form cystines Ext. coefficient 59360 Abs 0.1% (=1 g/l) 1.156, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.23 This classifies the protein as stable. Aliphatic index: 87.26 Grand average of hydropathicity (GRAVY): -0.472