ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTEQEDLATS GGGNATTGSG TNCQNQLQQC VRGNVTWELL PVHLRSVLHN NQRDYEKFVF 

        70         80         90        100        110        120 
NYSLKNQLRF RGNLAAKVFR REQRYYELLI QKSINGLGAF PYHLADIVTK GLRVTPFNYY 

       130        140        150        160        170        180 
LDVLGQLLQS DKSYDTLPNF TAADCLRVLG IGRNEYLALI SDMKTHTPRS LIFGSRPNPL 

       190        200        210        220        230        240 
DFLPRFPVRI HIEPWWRLDI GYVLEADIRY LSPAERGLLD DLIDFGAQPA GKCDHDVVHS 

       250        260        270        280        290        300 
LYRKGLIYLD VPISGEDRIS IPPLRNFVMN RVSGDYFENL LYKIFVSADE HMTIAELAQM 

       310        320        330        340        350        360 
LQLELDSVKQ AISFICRLGF AHRKEDLVNQ TNHSSWEGYN QQQTPDTPQI TPLNYNLHTS 

       370        380        390        400        410        420 
SSFEFDQSPK SPKTPKEREK DKDKDSSSIG YLSSDGNTSD FSFANLNTTP QERVNNSDEQ 

       430        440        450        460        470        480 
ELSSELEQED MSAPKHTAPS AAISAAVLPK SGKRVGFLFD STLTAFLMMG NLSPGLKNHA 

       490        500        510        520        530        540 
VTMFEVGKLC EESLDSFLAE LEQVSLLDAE GEGDVSRYFA HAVILRSTIC SLRHLLPGGL 

       550        560        570        580        590        600 
DLLRLECLEG LDQQTRDRVL EKKYKFIIAA SPLTASLSHT FSIPYFGQFL RSSDVAPMWS 

       610        620        630        640        650        660 
KLFYNHITGY GPPSLLLCRG TVLKTLPRLF LGYGKLLVNI LHSDAYVLNS ENFRSLNSQL 

       670        680        690        700        710        720 
KNGCVLLQGY GIRTAGALHY ESFPFQAADT RQAKWAAHRA VHKLSSLLDL RQQCGYITFL 

       730        740        750        760        770        780 
NTGVPDLGCE DYELQVRLKP AQRQKRTSIA APSKPNHVPT NEVTSFQLKS PDENHFAATP 

       790        800        810        820        830        840 
EHGPANEFTA PDCSQVLASE LAKCSSRADL VSQSSVEIEE ISPSVVQEED ATEEWTLLDV 

       850        860        870        880        890        900 
NFGVPLFDVD TNTRICEQLV QGLCSDANLE ALPAAASQAQ VLFLDFVQQC LYFEDDPARQ 

       910        920 
SVQAARPLPH PRINLAFENG HVCHWNGR 

References and documentation are available.

Number of amino acids: 928

Molecular weight: 103947.44

Theoretical pI: 5.61

Amino acid composition: 
Ala (A)  65	  7.0%
Arg (R)  50	  5.4%
Asn (N)  46	  5.0%
Asp (D)  55	  5.9%
Cys (C)  18	  1.9%
Gln (Q)  49	  5.3%
Glu (E)  56	  6.0%
Gly (G)  53	  5.7%
His (H)  27	  2.9%
Ile (I)  36	  3.9%
Leu (L) 117	 12.6%
Lys (K)  37	  4.0%
Met (M)  10	  1.1%
Phe (F)  45	  4.8%
Pro (P)  50	  5.4%
Ser (S)  78	  8.4%
Thr (T)  46	  5.0%
Trp (W)   8	  0.9%
Tyr (Y)  30	  3.2%
Val (V)  52	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 111
Total number of positively charged residues (Arg + Lys): 87

Atomic composition:

Carbon      C	      4627
Hydrogen    H	      7202
Nitrogen    N	      1272
Oxygen      O	      1400
Sulfur      S	        28

Formula: C4627H7202N1272O1400S28
Total number of atoms: 14529

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    89825
Abs 0.1% (=1 g/l)   0.864, assuming all pairs of Cys residues form cystines


Ext. coefficient    88700
Abs 0.1% (=1 g/l)   0.853, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.69
This classifies the protein as stable.



Aliphatic index: 87.55

Grand average of hydropathicity (GRAVY): -0.309