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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTGDSRSISE PSINLDPDNT SFSDENSDDF FMDNSYDIDE IDHSDESNRQ SVIVDSKVTV

70 80 90 100 110 120
PPSKHSTLTL SDSEDSDAKE QHQSLSRSSS KNVNIEDITE PKPDKPSGRT RGRSVMKESV

130 140 150 160 170 180
VEINSSESDL DEDKNFPRSR SRSRSSIRSI SPAGKYKRQK SSLLYTYDEN DDFFKELAKE

190 200 210 220 230 240
AKKSTTISKE STPDQRKRVY NIKFLSKLEG TINKAVQVKV LGKYEFSKIL PAALDGLMKS

250 260 270 280 290 300
YKIPKVMKDI YKVENVTLYW NNAKLLTFMT CNSLHIPQDF ENEVSDIDVT IVSKEYEKNF

310 320 330 340 350 360
EATLESKLKE EEAALLIKER QEMERKLEKK RNEQEESEYR EFESELKNVE ETQEIKENDT

370 380 390 400 410 420
VMNTKLLQEG GSLSGNSSSM EEVMRIALMG QDNKKIYVHV RRSTPFSKIA EYYRIQKQLP

430 440 450
QKTRVKLLFD HDELDMNECI ADQDMEDEDM VDVIID


References and documentation are available.

Number of amino acids: 456 Molecular weight: 52541.55 Theoretical pI: 4.96
Amino acid composition: 
Ala (A) 14 3.1% Arg (R) 23 5.0% Asn (N) 25 5.5% Asp (D) 40 8.8% Cys (C) 2 0.4% Gln (Q) 16 3.5% Glu (E) 51 11.2% Gly (G) 11 2.4% His (H) 6 1.3% Ile (I) 28 6.1% Leu (L) 32 7.0% Lys (K) 46 10.1% Met (M) 14 3.1% Phe (F) 14 3.1% Pro (P) 15 3.3% Ser (S) 56 12.3% Thr (T) 22 4.8% Trp (W) 1 0.2% Tyr (Y) 14 3.1% Val (V) 26 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 91 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 2269 Hydrogen H 3641 Nitrogen N 625 Oxygen O 772 Sulfur S 16 Formula: C2269H3641N625O772S16 Total number of atoms: 7323 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 26485 Abs 0.1% (=1 g/l) 0.504, assuming all pairs of Cys residues form cystines Ext. coefficient 26360 Abs 0.1% (=1 g/l) 0.502, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 53.22 This classifies the protein as unstable. Aliphatic index: 70.92 Grand average of hydropathicity (GRAVY): -0.919