ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTGLNGDDPD DYYLNLNQDE ESLLRSRHSV GSGAPHRQGS LVRPERSRLN NPDNPHFYYA 

        70         80         90        100        110        120 
QKTQEQMNHL DVLPSSTGVN PNATRRSGSL RSKGSVRSKF SGRETDSYLL QDMNTTDKKA 

       130        140        150        160        170        180 
SVKISDEGVA EDEFDKDGDV DNFEESSTQP INKSIKPLRK ETNDTLSFWQ MYCYFITFWA 

       190        200        210        220        230        240 
PAPILAFCGM PKKERQMAWR EKVALISVIL YIGAIVAFLT FGFTKTVCSS SKLRLKNNEV 

       250        260        270        280        290        300 
STEFVVINGK AYELDTSSRS GIQDVEVDSD TLYGPWSDAG KDASFLFQNV NGNCHNLITP 

       310        320        330        340        350        360 
KSNSSIPHDD DNNLAWYFPC KLKNQDGSSK PNFTVENYAG WNCHTSKEDR DAFYGLKSKA 

       370        380        390        400        410        420 
DVYFTWDGIK NSSRNLIVYN GDVLDLDLLD WLEKDDVDYP VVFDDLKTSN LQGYDLSLVL 

       430        440        450        460        470        480 
SNGHERKIAR CLSEIIKVGE VDSKTVGCIA SDVVLYVSLV FILSVVIIKF IIACYFRWTV 

       490        500        510        520        530        540 
ARKQGAYIVD NKTMDKHTND IEDWSNNIQT KAPLKEVDPH LRPKKYSKKS LGHKRASTFD 

       550        560        570        580        590        600 
LLKKHSSKMF QFNESVIDLD TSMSSSLQSS GSYRGMTTMT TQNAWKLSNE NKAVHSRNPS 

       610        620        630        640        650        660 
TLLPTSSMFW NKATSSPVPG SSLIQSLDST IIHPDIVQQP PLDFMPYGFP LIHTICFVTC 

       670        680        690        700        710        720 
YSEDEEGLRT TLDSLSTTDY PNSHKLLMVV CDGLIKGSGN DKTTPEIALG MMDDFVTPPD 

       730        740        750        760        770        780 
EVKPYSYVAV ASGSKRHNMA KIYAGFYKYD DSTIPPENQQ RVPIITIVKC GTPAEQGAAK 

       790        800        810        820        830        840 
PGNRGKRDSQ IILMSFLEKI TFDERMTQLE FQLLKNIWQI TGLMADFYET VLMVDADTKV 

       850        860        870        880        890        900 
FPDALTHMVA EMVKDPLIMG LCGETKIANK AQSWVTAIQV FEYYISHHQA KAFESVFGSV 

       910        920        930        940        950        960 
TCLPGCFSMY RIKSPKGSDG YWVPVLANPD IVERYSDNVT NTLHKKNLLL LGEDRFLSSL 

       970        980        990       1000       1010       1020 
MLKTFPKRKQ VFVPKAACKT IAPDKFKVLL SQRRRWINST VHNLFELVLI RDLCGTFCFS 

      1030       1040       1050       1060       1070       1080 
MQFVIGIELI GTMVLPLAIC FTIYVIIFAI VSKPTPVITL VLLAIILGLP GLIVVITATR 

      1090       1100       1110       1120       1130       1140 
WSYLWWMCVY ICALPIWNFV LPSYAYWKFD DFSWGDTRTI AGGNKKAQDE NEGEFDHSKI 

      1150       1160 
KMRTWREFER EDILNRKEES DSFVA 

References and documentation are available.

Number of amino acids: 1165

Molecular weight: 131601.23

Theoretical pI: 6.26

Amino acid composition: 
Ala (A)  59	  5.1%
Arg (R)  46	  3.9%
Asn (N)  59	  5.1%
Asp (D)  84	  7.2%
Cys (C)  22	  1.9%
Gln (Q)  35	  3.0%
Glu (E)  54	  4.6%
Gly (G)  62	  5.3%
His (H)  23	  2.0%
Ile (I)  73	  6.3%
Leu (L) 102	  8.8%
Lys (K)  83	  7.1%
Met (M)  30	  2.6%
Phe (F)  56	  4.8%
Pro (P)  55	  4.7%
Ser (S) 105	  9.0%
Thr (T)  73	  6.3%
Trp (W)  23	  2.0%
Tyr (Y)  41	  3.5%
Val (V)  80	  6.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 138
Total number of positively charged residues (Arg + Lys): 129

Atomic composition:

Carbon      C	      5904
Hydrogen    H	      9173
Nitrogen    N	      1549
Oxygen      O	      1755
Sulfur      S	        52

Formula: C5904H9173N1549O1755S52
Total number of atoms: 18433

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   188965
Abs 0.1% (=1 g/l)   1.436, assuming all pairs of Cys residues form cystines


Ext. coefficient   187590
Abs 0.1% (=1 g/l)   1.425, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.00
This classifies the protein as stable.



Aliphatic index: 83.56

Grand average of hydropathicity (GRAVY): -0.267