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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTHPVISLKP SYNSVIRGCP GLPDTLPRIE CQLRVRSNNS LPFKLVKIEI VLKTIEIYFN

70 80 90 100 110 120
KNLYSSNNSS FTPFNRPSDP SNGHSDTSNQ NISIHYKKNI VLSHPTHDGD DLNNDLIGID

130 140 150 160 170 180
IPLTIGLPDD IKETNYNPKF GKTQTFLDCT VFYTEVGGGS SNKKRNFLYP VNVERYTYLP

190 200 210 220 230 240
SPSYFRPINR SNITSPDQKF LISYSIENPC VSMNNDTLKL SISIRLNPFP NNATTPSSND

250 260 270 280 290 300
FDVSTPTLFS TKKKFKSKLK LKSITTQILE YLEILKNQSE FSSTQTTNIL QTSVRQVDQI

310 320 330 340 350 360
ISMNSMIFQF NLKIFTKDKI LQSFRSSESS CPETKVLINK IDDIPLQYHS SITTIGQHFN

370 380 390 400 410 420
VSHYLSIRFK FNKSLKNFEI NHPLIISFWS VSQLPLIENL ILQERQTAKF AKKFYKNFGR

430 440 450 460 470
IKNTSNNNNS SNCLEYPSLP PIIYNFNDPE TNNRFNILYS QKDPSRTDPS KLRRVPVIQ


References and documentation are available.

Number of amino acids: 479 Molecular weight: 54893.46 Theoretical pI: 9.43
Amino acid composition: 
Ala (A) 3 0.6% Arg (R) 19 4.0% Asn (N) 50 10.4% Asp (D) 22 4.6% Cys (C) 6 1.3% Gln (Q) 19 4.0% Glu (E) 17 3.5% Gly (G) 12 2.5% His (H) 9 1.9% Ile (I) 46 9.6% Leu (L) 42 8.8% Lys (K) 37 7.7% Met (M) 4 0.8% Phe (F) 29 6.1% Pro (P) 34 7.1% Ser (S) 58 12.1% Thr (T) 34 7.1% Trp (W) 1 0.2% Tyr (Y) 18 3.8% Val (V) 19 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2466 Hydrogen H 3873 Nitrogen N 661 Oxygen O 737 Sulfur S 10 Formula: C2466H3873N661O737S10 Total number of atoms: 7747 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 32695 Abs 0.1% (=1 g/l) 0.596, assuming all pairs of Cys residues form cystines Ext. coefficient 32320 Abs 0.1% (=1 g/l) 0.589, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.46 This classifies the protein as unstable. Aliphatic index: 83.78 Grand average of hydropathicity (GRAVY): -0.490