ProtParam
User-provided sequence:
10 20 30 40 50 60
MTHSKRWLEE HEKDPYVKRA KKEGYPSRAA YKLLEIHQKY KLFKPSMNVI DLGAAPGGWS
70 80 90 100 110 120
QVAKDLVGPK GVVIAIDLLP MQSMLDVIFI QGDFNEPEIF NQLEAIVAKK TLTGQVDLVI
130 140 150 160 170 180
SDMAPNISGI KNVDQSRSLH LVELAWDCAQ KLLARGGTFL VKVFQGPGVD RFLINLRPYF
190 200 210
NQVKFLKPSA SRSRSSEIYI LAGEFLGYNQ RV
References and
documentation are available.
Number of amino acids: 212
Molecular weight: 23861.75
Theoretical pI: 9.32
Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 1087
Hydrogen H 1722
Nitrogen N 290
Oxygen O 301
Sulfur S 6
Formula: C
1087H
1722N
290O
301S
6
Total number of atoms: 3406
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 26930
Abs 0.1% (=1 g/l) 1.129, assuming all pairs of Cys residues form cystines
Ext. coefficient 26930
Abs 0.1% (=1 g/l) 1.129, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 38.58
This classifies the protein as stable.
Aliphatic index: 98.40
Grand average of hydropathicity (GRAVY): -0.151