ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTIAHHCIFL VILAFLALIN VASGATEACL PAGQRKSGMN INFYQYSLKD SSTYSNAAYM 

        70         80         90        100        110        120 
AYGYASKTKL GSVGGQTDIS IDYNIPCVSS SGTFPCPQED SYGNWGCKGM GACSNSQGIA 

       130        140        150        160        170        180 
YWSTDLFGFY TTPTNVTLEM TGYFLPPQTG SYTFSFATVD DSAILSVGGS IAFECCAQEQ 

       190        200        210        220        230        240 
PPITSTNFTI NGIKPWDGSL PDNITGTVYM YAGYYYPLKV VYSNAVSWGT LPISVELPDG 

       250        260        270        280        290        300 
TTVSDNFEGY VYSFDDDLSQ SNCTIPDPSI HTTSTITTTT EPWTGTFTST STEMTTITDT 

       310        320        330        340        350        360 
NGQLTDETVI VIRTPTTAST ITTTTEPWTG TFTSTSTEMT TVTGTNGQPT DETVIVIRTP 

       370        380        390        400        410        420 
TSEGLITTTT EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL ITTTTEPWTG 

       430        440        450        460        470        480 
TFTSTSTEVT TITGTNGQPT DETVIVIRTP TSEGLITTTT EPWTGTFTST STEMTTVTGT 

       490        500        510        520        530        540 
NGQPTDETVI VIRTPTSEGL ISTTTEPWTG TFTSTSTEVT TITGTNGQPT DETVIVIRTP 

       550        560        570        580        590        600 
TSEGLITTTT EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL ITRTTEPWTG 

       610        620        630        640        650        660 
TFTSTSTEVT TITGTNGQPT DETVIVIRTP TTAISSSLSS SSGQITSSIT SSRPIITPFY 

       670        680        690        700        710        720 
PSNGTSVISS SVISSSVTSS LVTSSSFISS SVISSSTTTS TSIFSESSTS SVIPTSSSTS 

       730        740        750        760        770        780 
GSSESKTSSA SSSSSSSSIS SESPKSPTNS SSSLPPVTSA TTGQETASSL PPATTTKTSE 

       790        800        810        820        830        840 
QTTLVTVTSC ESHVCTESIS SAIVSTATVT VSGVTTEYTT WCPISTTETT KQTKGTTEQT 

       850        860        870        880        890        900 
KGTTEQTTET TKQTTVVTIS SCESDICSKT ASPAIVSTST ATINGVTTEY TTWCPISTTE 

       910        920        930        940        950        960 
SKQQTTLVTV TSCESGVCSE TTSPAIVSTA TATVNDVVTV YPTWRPQTTN EQSVSSKMNS 

       970        980        990       1000       1010       1020 
ATSETTTNTG AAETKTAVTS SLSRFNHAET QTASATDVIG HSSSVVSVSE TGNTMSLTSS 

      1030       1040       1050       1060       1070 
GLSTMSQQPR STPASSMVGS STASLEISTY AGSANSLLAG SGLSVFIASL LLAII 

References and documentation are available.

Number of amino acids: 1075

Molecular weight: 111981.60

Theoretical pI: 4.21

Amino acid composition: 
Ala (A)  47	  4.4%
Arg (R)  14	  1.3%
Asn (N)  32	  3.0%
Asp (D)  27	  2.5%
Cys (C)  17	  1.6%
Gln (Q)  31	  2.9%
Glu (E)  60	  5.6%
Gly (G)  71	  6.6%
His (H)   6	  0.6%
Ile (I)  72	  6.7%
Leu (L)  39	  3.6%
Lys (K)  18	  1.7%
Met (M)  15	  1.4%
Phe (F)  26	  2.4%
Pro (P)  57	  5.3%
Ser (S) 175	 16.3%
Thr (T) 257	 23.9%
Trp (W)  15	  1.4%
Tyr (Y)  25	  2.3%
Val (V)  71	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 87
Total number of positively charged residues (Arg + Lys): 32

Atomic composition:

Carbon      C	      4811
Hydrogen    H	      7633
Nitrogen    N	      1225
Oxygen      O	      1770
Sulfur      S	        32

Formula: C4811H7633N1225O1770S32
Total number of atoms: 15471

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   120750
Abs 0.1% (=1 g/l)   1.078, assuming all pairs of Cys residues form cystines


Ext. coefficient   119750
Abs 0.1% (=1 g/l)   1.069, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.77
This classifies the protein as stable.



Aliphatic index: 63.80

Grand average of hydropathicity (GRAVY): -0.153