ProtParam
User-provided sequence:
10 20 30 40 50 60
MTKSYMPLFR SPRQFKKIYF ILIPLILAVI ILHVFFDGFN KISEYSPTFI SNRILNHQDQ
70 80 90 100 110 120
QQKSEKSSDV ISSYFPSLAI YPKNFDNRVE FVNEPKNSKW IQYFGDSKTV LSNYITNQTY
130 140 150 160 170 180
TNHSIGLYSS STVRPPASSC KDILYERSFE ITKYRTLHDD LYKLATTLLY QLENDPAFQD
190 200 210 220 230 240
LSPFFNDRLP HIIMRGELHK HIYKFAGTSV WLEQHGVHLM LSRVIYSQQG KKNDPQLSLL
250 260 270 280 290 300
YAQVYDENWN ELNDIELIVP VINPNGERVY DSVKYPQFVA IPFYHNSEYI KSRWYGPEDT
310 320 330 340 350 360
RLILTKNKFG DDEPVIIFNS YHRQIKDMST EDDNNVHTKF EFYRSMFVGW LFQYQLGKLN
370 380 390 400 410 420
TDGIQDSKFN NVTFNKVKEL RIEGKERTSI EKNWTPFIDP DERNQISYYG NHNLGDNYVY
430 440 450 460 470 480
IVYQWNHLKI LKCELDNFID SSHSTCTMFF KDVETTQEVG PVRGGTELWP IKIDNNNNNN
490 500 510 520 530 540
NLNEDDLSTK QEPQQQRQLW IGFLRAHVKD CGCGGSMYRP NFLILEKLNS KFKLTYLSGS
550 560 570 580 590 600
INFNVSVYGW ANYDVVCAGH EANALIPNGI SMFDQDDDYL TLSMSVADQD NTLVHIHGVK
610 620 630 640 650 660
KLIYSLDHDW NGILKENKQI ECVVNNANDF CKAYADEHYK LGDSEAAVKE VKQKAKEEAE
670 680 690 700 710 720
KAKAEKEKAE KEKAEKEKAE KEKEEKEKEE KEEKEKAEKE KEEKEKAEKE LAEKELAEQK
730 740 750 760 770 780
DEDAKDEDKN EDEDDKEKND ESGLTEKSEV EENGENANEG GEDDGDGDGE EEKEDDDDID
VYNMRFNMQ
References and
documentation are available.
Number of amino acids: 789
Molecular weight: 91972.38
Theoretical pI: 4.97
Total number of negatively charged residues (Asp + Glu): 144
Total number of positively charged residues (Arg + Lys): 99
Atomic composition:
Carbon C 4095
Hydrogen H 6254
Nitrogen N 1082
Oxygen O 1293
Sulfur S 20
Formula: C
4095H
6254N
1082O
1293S
20
Total number of atoms: 12744
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 119110
Abs 0.1% (=1 g/l) 1.295, assuming all pairs of Cys residues form cystines
Ext. coefficient 118610
Abs 0.1% (=1 g/l) 1.290, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.11
This classifies the protein as unstable.
Aliphatic index: 71.65
Grand average of hydropathicity (GRAVY): -0.849