ProtParam
User-provided sequence:
10 20 30 40 50 60
MTLAELLGRS RIAQVANNHK PLTYTGKKFH PTHQIIETKP STLYRQEWGL KSAIPSKIKS
70 80 90 100 110 120
RYLVYNDLDT LERITTFEPR GGTQWNRLRF QEMGVPIVSN IGRQNPFFKY ISRPEDESHA
130 140 150 160 170 180
KLSLFKEMKG DTDISPAAMK KRLKKITALI RSFQDEFKEW LVENHPDELK LNSNKLEDYV
190 200 210 220 230 240
VKFLNKKLET KTNKKFNTEI IGTGGLSYSL PGKLKNSPNG VIQRTVVPGR ILNVVKENND
250 260 270 280 290 300
NKWLAAIGGF VADVVFFQSP PSSFNSMGDF IRMKTFLFEI LEASMEKNGS VSMHARLLEP
310 320 330 340
QNDKTREFFN KRPIYKPLTS RRARRPSVGN IQEANNLLNI IKGN
References and
documentation are available.
Number of amino acids: 344
Molecular weight: 39445.46
Theoretical pI: 9.95
Total number of negatively charged residues (Asp + Glu): 35
Total number of positively charged residues (Arg + Lys): 56
Atomic composition:
Carbon C 1772
Hydrogen H 2828
Nitrogen N 498
Oxygen O 505
Sulfur S 8
Formula: C
1772H
2828N
498O
505S
8
Total number of atoms: 5611
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 33920
Abs 0.1% (=1 g/l) 0.860
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 41.95
This classifies the protein as unstable.
Aliphatic index: 81.05
Grand average of hydropathicity (GRAVY): -0.581