ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTLQESDKFA TKAIHAGEHV DVHGSVIEPI SLSTTFKQSS PANPIGTYEY SRSQNPNREN 

        70         80         90        100        110        120 
LERAVAALEN AQYGLAFSSG SATTATILQS LPQGSHAVSI GDVYGGTHRY FTKVANAHGV 

       130        140        150        160        170        180 
ETSFTNDLLN DLPQLIKENT KLVWIETPTN PTLKVTDIQK VADLIKKHAA GQDVILVVDN 

       190        200        210        220        230        240 
TFLSPYISNP LNFGADIVVH SATKYINGHS DVVLGVLATN NKPLYERLQF LQNAIGAIPS 

       250        260        270        280        290        300 
PFDAWLTHRG LKTLHLRVRQ AALSANKIAE FLAADKENVV AVNYPGLKTH PNYDVVLKQH 

       310        320        330        340        350        360 
RDALGGGMIS FRIKGGAEAA SKFASSTRLF TLAESLGGIE SLLEVPAVMT HGGIPKEARE 

       370        380        390 
ASGVFDDLVR ISVGIEDTDD LLEDIKQALK QATN 

References and documentation are available.

Number of amino acids: 394

Molecular weight: 42542.08

Theoretical pI: 6.06

Amino acid composition: 
Ala (A)  41	 10.4%
Arg (R)  13	  3.3%
Asn (N)  22	  5.6%
Asp (D)  21	  5.3%
Cys (C)   0	  0.0%
Gln (Q)  15	  3.8%
Glu (E)  21	  5.3%
Gly (G)  28	  7.1%
His (H)  14	  3.6%
Ile (I)  24	  6.1%
Leu (L)  40	 10.2%
Lys (K)  22	  5.6%
Met (M)   3	  0.8%
Phe (F)  14	  3.6%
Pro (P)  17	  4.3%
Ser (S)  29	  7.4%
Thr (T)  28	  7.1%
Trp (W)   2	  0.5%
Tyr (Y)  10	  2.5%
Val (V)  30	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      1896
Hydrogen    H	      3010
Nitrogen    N	       522
Oxygen      O	       583
Sulfur      S	         3

Formula: C1896H3010N522O583S3
Total number of atoms: 6014

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    25900
Abs 0.1% (=1 g/l)   0.609

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.47
This classifies the protein as stable.



Aliphatic index: 95.84

Grand average of hydropathicity (GRAVY): -0.144