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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTLSKYSKPT LNDPNLFRES GYIDGKWVKG TDEVFEVVDP ASGEIIARVP EQPVSVVEEA

70 80 90 100 110 120
IDVAYETFKT YKNTTPRERA KWLRNMYNLM LENLDDLATI ITLENGKALG EAKGEIKYAA

130 140 150 160 170 180
SYFEWYAEEA PRLYGATIQP LNPHNRVFTI RQPVGVCGII CPWNFPSAMI TRKAAAALAV

190 200 210 220 230 240
GCTVVIKPDS QTPLSALAMA YLAEKAGFPK GSFNVILSHA NTPKLGKTLC ESPKVKKVTF

250 260 270 280 290 300
TGSTNVGKIL MKQSSSTLKK LSFELGGNAP FIVFEDADLD QALEQAMACK FRGLGQTCVC

310 320 330 340 350 360
ANRLYVHSSI IDKFAKLLAE RVKKFVIGHG LDPKTTHGCV INSSAIEKVE RHKQDAIDKG

370 380 390 400 410 420
AKVVLEGGRL TELGPNFYAP VILSHVPSTA IVSKEETFGP LCPIFSFDTM EEVVGYANDT

430 440 450 460 470 480
EFGLAAYVFS KNVNTLYTVS EALETGMVSC NTGVFSDCSI PFGGVKESGF GREGSLYGIE

490
DYTVLKTITI GNLPNSI


References and documentation are available.

Number of amino acids: 497 Molecular weight: 54189.25 Theoretical pI: 6.24
Amino acid composition: 
Ala (A) 42 8.5% Arg (R) 15 3.0% Asn (N) 23 4.6% Asp (D) 19 3.8% Cys (C) 11 2.2% Gln (Q) 9 1.8% Glu (E) 36 7.2% Gly (G) 39 7.8% His (H) 7 1.4% Ile (I) 30 6.0% Leu (L) 41 8.2% Lys (K) 37 7.4% Met (M) 9 1.8% Phe (F) 24 4.8% Pro (P) 26 5.2% Ser (S) 33 6.6% Thr (T) 35 7.0% Trp (W) 4 0.8% Tyr (Y) 17 3.4% Val (V) 40 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 52 Atomic composition: Carbon C 2437 Hydrogen H 3837 Nitrogen N 629 Oxygen O 725 Sulfur S 20 Formula: C2437H3837N629O725S20 Total number of atoms: 7648 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 47955 Abs 0.1% (=1 g/l) 0.885, assuming all pairs of Cys residues form cystines Ext. coefficient 47330 Abs 0.1% (=1 g/l) 0.873, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 30.28 This classifies the protein as stable. Aliphatic index: 87.51 Grand average of hydropathicity (GRAVY): -0.053