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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTMAANLARR LIGNRSTQIL GAVNSSSGAA SSVARAFCSS TTPITATLFP GDGIGPEIAE

70 80 90 100 110 120
SVKKVFTTAG VPIEWEEHYV GTEIDPRTQS FLTWESLESV RRNKVGLKGP MATPIGKGHR

130 140 150 160 170 180
SLNLTLRKEL NLYANVRPCY SLPGYKTRYD DVDLITIREN TEGEYSGLEH QVVRGVVESL

190 200 210 220 230 240
KIITRQASLR VAEYAFLYAK THGRERVSAI HKANIMQKTD GLFLKCCREV AEKYPEITYE

250 260 270 280 290 300
EVVIDNCCMM LVKNPALFDV LVMPNLYGDI ISDLCAGLVG GLGLTPSCNI GEDGVALAEA

310 320 330 340 350 360
VHGSAPDIAG KNLANPTALL LSGVMMLRHL KFNEQAEQIH SAIINTIAEG KYRTADLGGS

370
STTTEFTKAI CDHL


References and documentation are available.

Number of amino acids: 374 Molecular weight: 40624.58 Theoretical pI: 6.33
Amino acid composition: 
Ala (A) 34 9.1% Arg (R) 20 5.3% Asn (N) 17 4.5% Asp (D) 14 3.7% Cys (C) 9 2.4% Gln (Q) 7 1.9% Glu (E) 27 7.2% Gly (G) 31 8.3% His (H) 9 2.4% Ile (I) 25 6.7% Leu (L) 37 9.9% Lys (K) 18 4.8% Met (M) 9 2.4% Phe (F) 9 2.4% Pro (P) 15 4.0% Ser (S) 25 6.7% Thr (T) 28 7.5% Trp (W) 2 0.5% Tyr (Y) 12 3.2% Val (V) 26 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 41 Total number of positively charged residues (Arg + Lys): 38 Atomic composition: Carbon C 1787 Hydrogen H 2878 Nitrogen N 496 Oxygen O 546 Sulfur S 18 Formula: C1787H2878N496O546S18 Total number of atoms: 5725 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 29380 Abs 0.1% (=1 g/l) 0.723, assuming all pairs of Cys residues form cystines Ext. coefficient 28880 Abs 0.1% (=1 g/l) 0.711, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.55 This classifies the protein as stable. Aliphatic index: 93.90 Grand average of hydropathicity (GRAVY): -0.058