ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTMSENSRNL EAGLLLRKNQ NDINECRITA VVLFSTFVSV CGSFCFGCAA GYSSVAQTGI 

        70         80         90        100        110        120 
INDLGLSVAQ YSMFGSIMTF GGMIGAIFSG KVADLMGRKG TMWFAQIFCI FGWVAVALAK 

       130        140        150        160        170        180 
DSMWLDIGRL STGFAVGLLS YVIPVYIAEI TPKHVRGAFV FANQLMQSCG LSLFYVIGNF 

       190        200        210        220        230        240 
VHWRNLALIG LIPCALQVVT LFFIPESPRL LGKWGHEKEC RASLQSLRGD DADISEEANT 

       250        260        270        280        290        300 
IKETMILFDE GPKSRVMDLF QRRYAPSVVI GVGLMLLQQL SGSSGLMYYV GSVFDKGGFP 

       310        320        330        340        350        360 
SSIGSMILAV IMIPKALLGL ILVEKMGRRP LLLASTGGMC FFSLLLSFSF CFRSYGMLDE 

       370        380        390        400        410        420 
LTPIFTCIGV VGFISSFAVG MGGLPWIIMS EIFPMNVKVS AGTLVTLANW SFGWIVAFAY 

       430        440        450        460        470 
NFMLEWNASG TFLIFFTICG AGIVFIYAMV PETKGRTLED IQASLTDFLQ 

References and documentation are available.

Number of amino acids: 470

Molecular weight: 51299.50

Theoretical pI: 6.81

Amino acid composition: 
Ala (A)  34	  7.2%
Arg (R)  17	  3.6%
Asn (N)  14	  3.0%
Asp (D)  14	  3.0%
Cys (C)  12	  2.6%
Gln (Q)  13	  2.8%
Glu (E)  17	  3.6%
Gly (G)  49	 10.4%
His (H)   3	  0.6%
Ile (I)  38	  8.1%
Leu (L)  53	 11.3%
Lys (K)  14	  3.0%
Met (M)  23	  4.9%
Phe (F)  38	  8.1%
Pro (P)  14	  3.0%
Ser (S)  41	  8.7%
Thr (T)  21	  4.5%
Trp (W)   9	  1.9%
Tyr (Y)  11	  2.3%
Val (V)  35	  7.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      2355
Hydrogen    H	      3653
Nitrogen    N	       577
Oxygen      O	       633
Sulfur      S	        35

Formula: C2355H3653N577O633S35
Total number of atoms: 7253

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    66640
Abs 0.1% (=1 g/l)   1.299, assuming all pairs of Cys residues form cystines


Ext. coefficient    65890
Abs 0.1% (=1 g/l)   1.284, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.20
This classifies the protein as stable.



Aliphatic index: 104.34

Grand average of hydropathicity (GRAVY): 0.649