ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTNALLSIAV LLFSMLSLAQ AETHTFNWTT GWDYRNVDGL KSRPVITCNG QFPWPDITVN 

        70         80         90        100        110        120 
KGDRVQIYLT NGMNNTNTSM HFHGLFQNGT ASMDGVPFLT QCPIAPGSTM LYNFTVDYNV 

       130        140        150        160        170        180 
GTYWYHSHTD GQYEDGMKGL FIIKDDSFPY DYDEELSLSL SEWYHDLVTD LTKSFMSVYN 

       190        200        210        220        230        240 
PTGAEPIPQN LIVNNTMNLT WEVQPDTTYL LRIVNVGGFV SQYFWIEDHE MTVVEIDGIT 

       250        260        270        280        290        300 
TEKNVTDMLY ITVAQRYTVL VHTKNDTDKN FAIMQKFDDT MLDVIPSDLQ LNATSYMVYN 

       310        320        330        340        350        360 
KTAALPTQNY VDSIDNFLDD FYLQPYEKEA IYGEPDHVIT VDVVMDNLKN GVNYAFFNNI 

       370        380        390        400        410        420 
TYTAPKVPTL MTVLSSGDQA NNSEIYGSNT HTFILEKDEI VEIVLNNQDT GTHPFHLHGH 

       430        440        450        460        470        480 
AFQTIQRDRT YDDALGEVPH SFDPDNHPAF PEYPMRRDTL YVRPQSNFVI RFKADNPGVW 

       490        500        510        520        530        540 
FFHCHIEWHL LQGLGLVLVE DPFGIQDAHS QQLSENHLEV CQSCSVATEG NAAANTLDLT 

       550        560        570        580        590        600 
DLTGENVQHA FIPTGFTKKG IIAMTFSCFA GILGIITIAI YGMMDMEDAT EKVIRDLHVD 

       610        620        630 
PEVLLNEVDE NEERQVNEDR HSTEKHQFLT KAKRFF 

References and documentation are available.

Number of amino acids: 636

Molecular weight: 72360.07

Theoretical pI: 4.60

Amino acid composition: 
Ala (A)  31	  4.9%
Arg (R)  15	  2.4%
Asn (N)  45	  7.1%
Asp (D)  51	  8.0%
Cys (C)   6	  0.9%
Gln (Q)  27	  4.2%
Glu (E)  35	  5.5%
Gly (G)  35	  5.5%
His (H)  25	  3.9%
Ile (I)  37	  5.8%
Leu (L)  52	  8.2%
Lys (K)  21	  3.3%
Met (M)  21	  3.3%
Phe (F)  35	  5.5%
Pro (P)  28	  4.4%
Ser (S)  30	  4.7%
Thr (T)  58	  9.1%
Trp (W)   9	  1.4%
Tyr (Y)  28	  4.4%
Val (V)  47	  7.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 86
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      3243
Hydrogen    H	      4885
Nitrogen    N	       833
Oxygen      O	       997
Sulfur      S	        27

Formula: C3243H4885N833O997S27
Total number of atoms: 9985

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    91595
Abs 0.1% (=1 g/l)   1.266, assuming all pairs of Cys residues form cystines


Ext. coefficient    91220
Abs 0.1% (=1 g/l)   1.261, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.24
This classifies the protein as stable.



Aliphatic index: 80.88

Grand average of hydropathicity (GRAVY): -0.283