ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTPEQKAKLE ANRKLAIERL RKRGILSSDQ LNRIESRNEP LKTRPLAVTS GSNRDDNAAA 

        70         80         90        100        110        120 
AVHVPNHNGQ PSALANTNTN TTSLYGSGVV DGSKRDASVL DKRPTDRIRP SIRKQDYIEY 

       130        140        150        160        170        180 
DFATMQNLNG GYINPKDKLP NSDFTDDQEF ESEFGSKKQK TLQDWKKEQL ERKMLYENAP 

       190        200        210        220        230        240 
PPEHISKAPK CIECHINIEM DPVLHDVFKL QVCKQCSKEH PEKYALLTKT ECKEDYFLTD 

       250        260        270        280        290        300 
PELNDEDLFH RLEKPNPHSG TFARMQLFVR CEVEAFAFKK WGGEEGLDEE WQRREEGKAH 

       310        320        330        340        350        360 
RREKKYEKKI KEMRLKTRAQ EYTNRLREKK HGKAHIHHFS DPVDGGIDED GYQIQRRRCT 

       370 
DCGLETEEID I 

References and documentation are available.

Number of amino acids: 371

Molecular weight: 43038.31

Theoretical pI: 6.91

Amino acid composition: 
Ala (A)  21	  5.7%
Arg (R)  28	  7.5%
Asn (N)  19	  5.1%
Asp (D)  27	  7.3%
Cys (C)   8	  2.2%
Gln (Q)  16	  4.3%
Glu (E)  39	 10.5%
Gly (G)  19	  5.1%
His (H)  13	  3.5%
Ile (I)  17	  4.6%
Leu (L)  28	  7.5%
Lys (K)  37	 10.0%
Met (M)   6	  1.6%
Phe (F)  12	  3.2%
Pro (P)  19	  5.1%
Ser (S)  18	  4.9%
Thr (T)  19	  5.1%
Trp (W)   3	  0.8%
Tyr (Y)  10	  2.7%
Val (V)  12	  3.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 66
Total number of positively charged residues (Arg + Lys): 65

Atomic composition:

Carbon      C	      1868
Hydrogen    H	      2966
Nitrogen    N	       556
Oxygen      O	       586
Sulfur      S	        14

Formula: C1868H2966N556O586S14
Total number of atoms: 5990

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    31900
Abs 0.1% (=1 g/l)   0.741, assuming all pairs of Cys residues form cystines


Ext. coefficient    31400
Abs 0.1% (=1 g/l)   0.730, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 51.59
This classifies the protein as unstable.



Aliphatic index: 62.35

Grand average of hydropathicity (GRAVY): -1.107