ProtParam
User-provided sequence:
10 20 30 40 50 60
MTPLLQAEAK MNTSLYLTES IQQHEFNLTS PQSFYSSPSV PNSKNNSGIF SYNTANNSRV
70 80 90 100 110 120
SSSDEFTTQQ DGMNTIMYKN NISKTFEDDI FYCPRSLLTP EEQVVYQEID KYYMEQALLT
130 140 150
QLQISQTYSS TPKEEKIVKF NPYTSKSFSP ASSE
References and
documentation are available.
Number of amino acids: 154
Molecular weight: 17602.44
Theoretical pI: 4.73
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 11
Atomic composition:
Carbon C 775
Hydrogen H 1185
Nitrogen N 195
Oxygen O 261
Sulfur S 6
Formula: C
775H
1185N
195O
261S
6
Total number of atoms: 2422
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14900
Abs 0.1% (=1 g/l) 0.846, assuming all pairs of Cys residues form cystines
Ext. coefficient 14900
Abs 0.1% (=1 g/l) 0.846, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 70.34
This classifies the protein as unstable.
Aliphatic index: 58.25
Grand average of hydropathicity (GRAVY): -0.712