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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTPLLQAEAK MNTSLYLTES IQQHEFNLTS PQSFYSSPSV PNSKNNSGIF SYNTANNSRV

70 80 90 100 110 120
SSSDEFTTQQ DGMNTIMYKN NISKTFEDDI FYCPRSLLTP EEQVVYQEID KYYMEQALLT

130 140 150
QLQISQTYSS TPKEEKIVKF NPYTSKSFSP ASSE


References and documentation are available.

Number of amino acids: 154 Molecular weight: 17602.44 Theoretical pI: 4.73
Amino acid composition: 
Ala (A) 5 3.2% Arg (R) 2 1.3% Asn (N) 12 7.8% Asp (D) 5 3.2% Cys (C) 1 0.6% Gln (Q) 12 7.8% Glu (E) 12 7.8% Gly (G) 2 1.3% His (H) 1 0.6% Ile (I) 8 5.2% Leu (L) 10 6.5% Lys (K) 9 5.8% Met (M) 5 3.2% Phe (F) 8 5.2% Pro (P) 9 5.8% Ser (S) 24 15.6% Thr (T) 14 9.1% Trp (W) 0 0.0% Tyr (Y) 10 6.5% Val (V) 5 3.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 17 Total number of positively charged residues (Arg + Lys): 11 Atomic composition: Carbon C 775 Hydrogen H 1185 Nitrogen N 195 Oxygen O 261 Sulfur S 6 Formula: C775H1185N195O261S6 Total number of atoms: 2422 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14900 Abs 0.1% (=1 g/l) 0.846, assuming all pairs of Cys residues form cystines Ext. coefficient 14900 Abs 0.1% (=1 g/l) 0.846, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 70.34 This classifies the protein as unstable. Aliphatic index: 58.25 Grand average of hydropathicity (GRAVY): -0.712