ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTPSTPPRSR GTRYLAQPSG NTSSSALMQG QKTPQKPSQN LVPVTPSTTK SFKNAPLLAP 

        70         80         90        100        110        120 
PNSNMGMTSP FNGLTSPQRS PFPKSSVKRT LFQFESHDNG TVREEQEPLG RVNRILFPTQ 

       130        140        150        160        170        180 
QNVDIDAAEE EEEGEVLLPP SRPTSARQLH LSLERDEFDQ THRKKIIKDV PGTPSDKVIT 

       190        200        210        220        230        240 
FELAKNWNNN SPKNDARSQE SEDEEDIIIN PVRVGKNPFA SDELVTQEIR NERKRAMLRE 

       250        260        270        280 
NPDIEDVITY VNKKGEVVEK RRLTDEEKRR FKPKALFQSR DQEH 

References and documentation are available.

Number of amino acids: 284

Molecular weight: 32222.98

Theoretical pI: 7.89

Amino acid composition: 
Ala (A)  12	  4.2%
Arg (R)  23	  8.1%
Asn (N)  19	  6.7%
Asp (D)  15	  5.3%
Cys (C)   0	  0.0%
Gln (Q)  16	  5.6%
Glu (E)  27	  9.5%
Gly (G)  11	  3.9%
His (H)   4	  1.4%
Ile (I)  11	  3.9%
Leu (L)  19	  6.7%
Lys (K)  20	  7.0%
Met (M)   5	  1.8%
Phe (F)  11	  3.9%
Pro (P)  27	  9.5%
Ser (S)  25	  8.8%
Thr (T)  20	  7.0%
Trp (W)   1	  0.4%
Tyr (Y)   2	  0.7%
Val (V)  16	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1394
Hydrogen    H	      2245
Nitrogen    N	       417
Oxygen      O	       451
Sulfur      S	         5

Formula: C1394H2245N417O451S5
Total number of atoms: 4512

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.263

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 65.74
This classifies the protein as unstable.



Aliphatic index: 61.76

Grand average of hydropathicity (GRAVY): -1.050