ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTPYAVAITV ALLIVTVSAL QVNNSCVAFP PSNLRGKNGD GTNEQYATAL LSIPWNGPPE 

        70         80         90        100        110        120 
SLRDINLIEL EPQVALYLLE NYINHYYNTT RDNKCPNNHY LMGGQLGSSS DNRSLNDPQT 

       130        140        150        160 
MLWPEKKEDE KNCQETFKGA CSCTKRFCKG YFSVNIFGIN LNISYSSGK 

References and documentation are available.

Number of amino acids: 169

Molecular weight: 18809.23

Theoretical pI: 6.10

Amino acid composition: 
Ala (A)   9	  5.3%
Arg (R)   5	  3.0%
Asn (N)  19	 11.2%
Asp (D)   6	  3.6%
Cys (C)   6	  3.6%
Gln (Q)   6	  3.6%
Glu (E)   9	  5.3%
Gly (G)  11	  6.5%
His (H)   2	  1.2%
Ile (I)   9	  5.3%
Leu (L)  17	 10.1%
Lys (K)   9	  5.3%
Met (M)   3	  1.8%
Phe (F)   5	  3.0%
Pro (P)  10	  5.9%
Ser (S)  14	  8.3%
Thr (T)  10	  5.9%
Trp (W)   2	  1.2%
Tyr (Y)   9	  5.3%
Val (V)   8	  4.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 15
Total number of positively charged residues (Arg + Lys): 14

Atomic composition:

Carbon      C	       829
Hydrogen    H	      1288
Nitrogen    N	       224
Oxygen      O	       258
Sulfur      S	         9

Formula: C829H1288N224O258S9
Total number of atoms: 2608

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    24785
Abs 0.1% (=1 g/l)   1.318, assuming all pairs of Cys residues form cystines


Ext. coefficient    24410
Abs 0.1% (=1 g/l)   1.298, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 55.24
This classifies the protein as unstable.



Aliphatic index: 79.05

Grand average of hydropathicity (GRAVY): -0.393