ProtParam
User-provided sequence:
10 20 30 40 50 60
MTRLLSRTFP SVKLRDSNPK APEFKNLKNS QTQVPIPSSS SPQENSKIPK SKSWSVYLIL
70 80 90 100 110 120
STTEPIKTYV GITTDFSRRL KQHNGEIRGG AKASSAGRPW LCACIITGFT CLSQASSFES
130 140 150 160 170
KWKIFTRKLP RRKKDEDMSQ SDALLQHRRR ALNKVEESLD CSYLETDWKI
References and
documentation are available.
Number of amino acids: 170
Molecular weight: 19353.17
Theoretical pI: 9.94
Total number of negatively charged residues (Asp + Glu): 16
Total number of positively charged residues (Arg + Lys): 30
Atomic composition:
Carbon C 852
Hydrogen H 1377
Nitrogen N 247
Oxygen O 255
Sulfur S 6
Formula: C
852H
1377N
247O
255S
6
Total number of atoms: 2737
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 26720
Abs 0.1% (=1 g/l) 1.381, assuming all pairs of Cys residues form cystines
Ext. coefficient 26470
Abs 0.1% (=1 g/l) 1.368, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 65.39
This classifies the protein as unstable.
Aliphatic index: 70.59
Grand average of hydropathicity (GRAVY): -0.695