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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTRTVSMSTA INEAMKISMR RDENVILIGE DVAGGAQVDH LQDDEAWGGV LGVTKGLVQE

70 80 90 100 110 120
FGRNRILDTP ISEAGYMGAA MAAAATGLRP IAELMFNDFI GSCLDQVLNQ GAKFRYMFGG

130 140 150 160 170 180
KAKVPVTVRT MHGAGFSAAA QHSQSLYALF TSIPGIKVVV PSTPYDAKGL LLAAIEDDDP

190 200 210 220 230 240
VIFFEDKTLY NMKGEVPEGY YTIPLGKADI KREGSDVTIV AIGKQVHTAL AAAEQLAKKG

250 260 270 280 290 300
LEVEVIDPRS LSPLDEDTIL SSVEKTNRLI VIDEANPRCS IATDIAAIVA DRGFDLLDAP

310 320 330 340
IKRITAPHTP VPFSPPLEKL YLPTPEKVIE TVSEMIGDQS LLHV


References and documentation are available.

Number of amino acids: 344 Molecular weight: 37007.53 Theoretical pI: 4.92
Amino acid composition: 
Ala (A) 37 10.8% Arg (R) 14 4.1% Asn (N) 8 2.3% Asp (D) 24 7.0% Cys (C) 2 0.6% Gln (Q) 10 2.9% Glu (E) 22 6.4% Gly (G) 27 7.8% His (H) 6 1.7% Ile (I) 27 7.8% Leu (L) 30 8.7% Lys (K) 18 5.2% Met (M) 11 3.2% Phe (F) 11 3.2% Pro (P) 20 5.8% Ser (S) 19 5.5% Thr (T) 21 6.1% Trp (W) 1 0.3% Tyr (Y) 8 2.3% Val (V) 28 8.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1647 Hydrogen H 2647 Nitrogen N 435 Oxygen O 503 Sulfur S 13 Formula: C1647H2647N435O503S13 Total number of atoms: 5245 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17545 Abs 0.1% (=1 g/l) 0.474, assuming all pairs of Cys residues form cystines Ext. coefficient 17420 Abs 0.1% (=1 g/l) 0.471, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.10 This classifies the protein as stable. Aliphatic index: 98.98 Grand average of hydropathicity (GRAVY): 0.047