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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSASITNTG NETMNLPQMR SIWLDEDEEA EKLYGLQAQQ FMGSDDEENL GITFINSDKP

70 80 90 100 110 120
VLSNKKNIEL PPLSPNSHPS CHHRRSNSNS AKSKESSSSS SSANKTNHKK VFLKLNLLKK

130 140 150 160 170 180
KLLGAQPDIR GKGISTPFDF QHISHADTRN GFQDEQLQEP SSLSTEIKDD YTSSSSKRDS

190 200 210 220 230 240
KSLNKAFVTE RIPANRESKL ISRSHENKTS RLSVARSISV TSSNYSKNTQ GNNHSINGRV

250 260 270 280 290 300
VSTSTMATSI FEYSPNASPK QFKNKSHALG HRYTNSTDSS ESSLDFLKNY NFPTLLEDKP

310 320 330 340 350 360
ILDFLPRSQR SSAYRSLLET PNSNKDSAKA FFPSRQSPLP KRRNSIATPS PQSKFSYSDS

370 380
PVNHRKSFDD VLYSFNQLEP LQT


References and documentation are available.

Number of amino acids: 383 Molecular weight: 42852.36 Theoretical pI: 9.48
Amino acid composition: 
Ala (A) 17 4.4% Arg (R) 20 5.2% Asn (N) 32 8.4% Asp (D) 20 5.2% Cys (C) 1 0.3% Gln (Q) 16 4.2% Glu (E) 20 5.2% Gly (G) 11 2.9% His (H) 11 2.9% Ile (I) 16 4.2% Leu (L) 32 8.4% Lys (K) 31 8.1% Met (M) 5 1.3% Phe (F) 17 4.4% Pro (P) 23 6.0% Ser (S) 69 18.0% Thr (T) 23 6.0% Trp (W) 1 0.3% Tyr (Y) 9 2.3% Val (V) 9 2.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 40 Total number of positively charged residues (Arg + Lys): 51 Atomic composition: Carbon C 1853 Hydrogen H 2939 Nitrogen N 545 Oxygen O 613 Sulfur S 6 Formula: C1853H2939N545O613S6 Total number of atoms: 5956 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 18910 Abs 0.1% (=1 g/l) 0.441, assuming all pairs of Cys residues form cystines Ext. coefficient 18910 Abs 0.1% (=1 g/l) 0.441, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 64.57 This classifies the protein as unstable. Aliphatic index: 60.13 Grand average of hydropathicity (GRAVY): -0.934