ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSATDKSID RLVVNAKTRR RNSSVGKIDL GDTVPGFAAM PESAASKNEA KKRMKALTGD 

        70         80         90        100        110        120 
SKKDSDLLWK VWFSYREMNY RHSWLTPFFI LVCVYSAYFL SGNRTESNPL HMFVAISYQV 

       130        140        150        160        170        180 
DGTDSYAKGI KDLSFVFFYM IFFTFLREFL MDVVIRPFTV YLNVTSEHRQ KRMLEQMYAI 

       190        200        210        220        230        240 
FYCGVSGPFG LYIMYHSDLW LFKTKPMYRT YPVITNPFLF KIFYLGQAAF WAQQACVLVL 

       250        260        270        280        290        300 
QLEKPRKDYK ELVFHHIVTL LLIWSSYVFH FTKMGLAIYI TMDVSDFFLS LSKTLNYLNS 

       310        320        330        340        350        360 
VFTPFVFGLF VFFWIYLRHV VNIRILWSVL TEFRHEGNYV LNFATQQYKC WISLPIVFVL 

       370        380        390        400        410 
IAALQLVNLY WLFLILRILY RLIWQGIQKD ERSDSDSDES AENEESKEKC E 

References and documentation are available.

Number of amino acids: 411

Molecular weight: 48454.50

Theoretical pI: 9.00

Amino acid composition: 
Ala (A)  21	  5.1%
Arg (R)  20	  4.9%
Asn (N)  15	  3.6%
Asp (D)  19	  4.6%
Cys (C)   5	  1.2%
Gln (Q)  12	  2.9%
Glu (E)  18	  4.4%
Gly (G)  15	  3.6%
His (H)   9	  2.2%
Ile (I)  25	  6.1%
Leu (L)  46	 11.2%
Lys (K)  25	  6.1%
Met (M)  13	  3.2%
Phe (F)  36	  8.8%
Pro (P)  12	  2.9%
Ser (S)  32	  7.8%
Thr (T)  21	  5.1%
Trp (W)  11	  2.7%
Tyr (Y)  24	  5.8%
Val (V)  32	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      2270
Hydrogen    H	      3414
Nitrogen    N	       552
Oxygen      O	       590
Sulfur      S	        18

Formula: C2270H3414N552O590S18
Total number of atoms: 6844

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    96510
Abs 0.1% (=1 g/l)   1.992, assuming all pairs of Cys residues form cystines


Ext. coefficient    96260
Abs 0.1% (=1 g/l)   1.987, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.16
This classifies the protein as unstable.



Aliphatic index: 95.06

Grand average of hydropathicity (GRAVY): 0.123