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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSDPVNTNI SSPTLTDRNA DESWELLKRE FNTLFSNLKT DSKEEGNFTD NKGVIAKKPI

70 80 90 100 110 120
VLQDNDDSDF TQNQGKVATA TSTTSDRSFK RTLGSIEMKK RYVKKNCQAK FVFNTLEGKE

130 140 150 160 170 180
VCSKILQHTL GLLSLLLLTR KIRLLNFSSK LRLVIQQLSL FRYYLRFGNF AINLYKIIKR

190 200 210 220 230 240
FRWLREMKKL HYKDQSILFY FKNFRFFDII EAFYNLTDEL ILFHKLQSMF GKKNTSHANT

250 260 270 280 290 300
NRLMTFVKEQ HYILWEVLNI LAINKNIEQW RQLIRDEIYL SIYNTSGNAI KEYELKYKLP

310 320 330 340 350 360
TNDKVNLELR KNNITLDFYK IILNLLSNLI NIKGKRDKYN SELAYEIISV GSGVTELLKL

370
WNRAKVTSAN EHTSAV


References and documentation are available.

Number of amino acids: 376 Molecular weight: 44131.00 Theoretical pI: 9.67
Amino acid composition: 
Ala (A) 14 3.7% Arg (R) 20 5.3% Asn (N) 34 9.0% Asp (D) 17 4.5% Cys (C) 2 0.5% Gln (Q) 12 3.2% Glu (E) 22 5.9% Gly (G) 12 3.2% His (H) 6 1.6% Ile (I) 29 7.7% Leu (L) 50 13.3% Lys (K) 39 10.4% Met (M) 5 1.3% Phe (F) 22 5.9% Pro (P) 4 1.1% Ser (S) 27 7.2% Thr (T) 26 6.9% Trp (W) 5 1.3% Tyr (Y) 15 4.0% Val (V) 15 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 2003 Hydrogen H 3184 Nitrogen N 538 Oxygen O 569 Sulfur S 7 Formula: C2003H3184N538O569S7 Total number of atoms: 6301 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 49975 Abs 0.1% (=1 g/l) 1.132, assuming all pairs of Cys residues form cystines Ext. coefficient 49850 Abs 0.1% (=1 g/l) 1.130, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.45 This classifies the protein as unstable. Aliphatic index: 97.23 Grand average of hydropathicity (GRAVY): -0.396