ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSKPSTSDG RAHSISHVPG THMRGTSASH SPRPFRPCAD CTCSPGLLSR QGRRASLFLR 

        70         80         90        100        110        120 
QLENSRRSSS MLLNELKGAG GGSSAGNGSV YSCDSLCAVN REVNTTDRLL KLRQEMKKHD 

       130        140        150        160        170        180 
LCCYIVPSCD EHQSEYVSLR DQRRAFISGF SGSAGVACIT RDLLNFNDDH PDGKSILSTD 

       190        200        210        220        230        240 
GRYFNQARQE LDYNWTLLRQ NEDPITWQEW CVREALEMAK GLGNKEGMVL KIGIDPKLIT 

       250        260        270        280        290        300 
FNDYVSFRKM IDTKYDAKGK VELVPVEENL VDSIWPDFET LPERPCNDLL LLKYEFHGEE 

       310        320        330        340        350        360 
FKDKKEKLLK KLNDKASSAT TGRNTFIVVA LDEICWLLNL RGSDIDYNPV FFSYVAINED 

       370        380        390        400        410        420 
ETILFTNNPF NDDISEYFKI NGIEVRPYEQ IWEHLTKITS QASSAEHEFL IPDSASWQMV 

       430        440        450        460        470        480 
RCLNTSTNAN GAIAKKMTAQ NFAIIHSPID VLKSIKNDIE IKNAHKAQVK DAVCLVQYFA 

       490        500        510        520        530        540 
WLEQQLVGRE ALIDEYRAAE KLTEIRKTQR NFMGNSFETI SSTGSNAAII HYSPPVENSS 

       550        560        570        580        590        600 
MIDPTKIYLC DSGSQFLEGT TDITRTIHLT KPTKEEMDNY TLVLKGGLAL ERLIFPENTP 

       610        620        630        640        650        660 
GFNIDAIARQ FLWSRGLDYK HGTGHGIGSF LNVHEGPMGV GFRPHLMNFP LRAGNIISNE 

       670        680        690        700        710        720 
PGYYKDGEYG IRIESDMLIK KATEKGNFLK FENMTVVPYC RKLINTKLLN EEEKTQINEY 

       730        740 
HARVWRTIVH FLQPQSISYK WLKRETSPL 

References and documentation are available.

Number of amino acids: 749

Molecular weight: 84924.37

Theoretical pI: 6.40

Amino acid composition: 
Ala (A)  41	  5.5%
Arg (R)  42	  5.6%
Asn (N)  45	  6.0%
Asp (D)  42	  5.6%
Cys (C)  16	  2.1%
Gln (Q)  23	  3.1%
Glu (E)  54	  7.2%
Gly (G)  47	  6.3%
His (H)  20	  2.7%
Ile (I)  51	  6.8%
Leu (L)  69	  9.2%
Lys (K)  48	  6.4%
Met (M)  16	  2.1%
Phe (F)  32	  4.3%
Pro (P)  32	  4.3%
Ser (S)  59	  7.9%
Thr (T)  44	  5.9%
Trp (W)  11	  1.5%
Tyr (Y)  24	  3.2%
Val (V)  33	  4.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 96
Total number of positively charged residues (Arg + Lys): 90

Atomic composition:

Carbon      C	      3761
Hydrogen    H	      5892
Nitrogen    N	      1042
Oxygen      O	      1137
Sulfur      S	        32

Formula: C3761H5892N1042O1137S32
Total number of atoms: 11864

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    97260
Abs 0.1% (=1 g/l)   1.145, assuming all pairs of Cys residues form cystines


Ext. coefficient    96260
Abs 0.1% (=1 g/l)   1.133, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.52
This classifies the protein as stable.



Aliphatic index: 80.73

Grand average of hydropathicity (GRAVY): -0.453