ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSKTSESGT GTQSTIVQLR NLPDLTEISH LEIDAPVVEI LKKTVLFQLN SLNICISNFA 

        70         80         90        100        110        120 
LDELVNLVTV QMDGMFRNLH NLTLLQRRSQ ASQADLKLLL REFNLDAPSL YQQFQASEFI 

       130        140        150        160        170        180 
KSKHSTEYEK LMSWSSLAAL PHNEEDEEDE LNNIEEQQNE INVLLPPSNP LEKQIPSWLP 

       190        200        210        220        230        240 
NFPPDHTYKF TPEFNHPITD LKTIKKEIVK ESQESEKALL NLNKSLSHIS SASNTPQPPG 

       250        260        270        280        290        300 
LDDEDAIEQQ LEIWGNALEE RKPTITEKSF NENNIEQYAK YRVELARERV TKFEVNQLKR 

       310        320        330        340        350        360 
TKNPFLKISE TLYLPESPHQ SHKTIQKTIE LQFRKSMTLF MHNLPKVQKL KKEKIRMAKE 

       370        380        390        400        410        420 
ERAKSLKRRQ EELISQRTKR EQDEGHDLEL LLNNEHARDA ADDTTTPNAL NNSTIVINTN 

       430        440        450        460        470        480 
AEDEDDDINL FGILGSSEDE NEMSSMPAEN LVAESEPPTM TAQDTTNTTP VAHNTTNIDA 

       490        500        510 
TTSHSPHSTP NENAPTSPPA DIATDHDITM 

References and documentation are available.

Number of amino acids: 510

Molecular weight: 57985.74

Theoretical pI: 4.95

Amino acid composition: 
Ala (A)  29	  5.7%
Arg (R)  18	  3.5%
Asn (N)  41	  8.0%
Asp (D)  28	  5.5%
Cys (C)   1	  0.2%
Gln (Q)  27	  5.3%
Glu (E)  55	 10.8%
Gly (G)   8	  1.6%
His (H)  16	  3.1%
Ile (I)  30	  5.9%
Leu (L)  56	 11.0%
Lys (K)  34	  6.7%
Met (M)  11	  2.2%
Phe (F)  15	  2.9%
Pro (P)  31	  6.1%
Ser (S)  42	  8.2%
Thr (T)  43	  8.4%
Trp (W)   3	  0.6%
Tyr (Y)   6	  1.2%
Val (V)  16	  3.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 83
Total number of positively charged residues (Arg + Lys): 52

Atomic composition:

Carbon      C	      2526
Hydrogen    H	      4035
Nitrogen    N	       701
Oxygen      O	       836
Sulfur      S	        12

Formula: C2526H4035N701O836S12
Total number of atoms: 8110

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    25440
Abs 0.1% (=1 g/l)   0.439, assuming all pairs of Cys residues form cystines


Ext. coefficient    25440
Abs 0.1% (=1 g/l)   0.439, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 59.79
This classifies the protein as unstable.



Aliphatic index: 80.55

Grand average of hydropathicity (GRAVY): -0.760