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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSLTNAVFK RYLAVTPSAH QALKTRIKKK SSSFDKFFPQ QSNSRKKQWE TLNEDKASWF

70 80 90 100 110 120
KRKYAHVHAR EQDRAADPYG KKKAHVEKLK EIKNQAKLNQ KSHKSKFQNK DIALKLMNDN

130 140 150 160 170 180
PIFEYVYGTN SVYAALLNPS RNCHSRLLYH GTIPSKFLQI VDELKVTTEL VDKHRLNLLT

190 200 210 220 230 240
NYGVHNNIAL ETKPLQPVEI AYLGDMDTSS AALSIHELGF NNENIPHELP YGTKTDAKKF

250 260 270 280 290 300
PLGLYLDEIT DPHNIGAIIR SAYFLGVDFI VMSRRNCSPL TPVVSKTSSG ALELLPIFYV

310 320 330 340 350 360
DKPLEFFTKS QEMGGWTFIT SHLANATSEK YTVGKTISMH DLNGLCNELP VVLVVGNESQ

370 380 390 400 410
GVRTNLKMRS DFFVEIPFGG IEKGNRAPEP IVDSLNVSVA TALLIDNILT CK


References and documentation are available.

Number of amino acids: 412 Molecular weight: 46387.22 Theoretical pI: 9.23
Amino acid composition: 
Ala (A) 27 6.6% Arg (R) 15 3.6% Asn (N) 28 6.8% Asp (D) 19 4.6% Cys (C) 4 1.0% Gln (Q) 12 2.9% Glu (E) 23 5.6% Gly (G) 20 4.9% His (H) 14 3.4% Ile (I) 23 5.6% Leu (L) 43 10.4% Lys (K) 38 9.2% Met (M) 7 1.7% Phe (F) 19 4.6% Pro (P) 20 4.9% Ser (S) 31 7.5% Thr (T) 26 6.3% Trp (W) 3 0.7% Tyr (Y) 14 3.4% Val (V) 26 6.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 42 Total number of positively charged residues (Arg + Lys): 53 Atomic composition: Carbon C 2086 Hydrogen H 3298 Nitrogen N 566 Oxygen O 608 Sulfur S 11 Formula: C2086H3298N566O608S11 Total number of atoms: 6569 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 37610 Abs 0.1% (=1 g/l) 0.811, assuming all pairs of Cys residues form cystines Ext. coefficient 37360 Abs 0.1% (=1 g/l) 0.805, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.21 This classifies the protein as stable. Aliphatic index: 87.33 Grand average of hydropathicity (GRAVY): -0.365