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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSPDDVPPL KPPPSFSPAT SILPSKSRYS DSLQDSQSLI HSLSEPSLDH RSLSDLQSVA

70 80 90 100 110 120
SSEVTSRSSS PDRRLSRSTL RLSRSSTATP LGSQIGGSDD VRSIIIRAFS PTIGVCASPD

130 140 150 160 170 180
TDALIQRKGF KGGFFELIRP FGERITGKVV IRDGVGSSRT WDDFGVRFAE LSGQDPGGRK

190 200 210 220 230 240
GGDVPAAAAQ LEEVLEKHLE SADQPLDSWV RGSDPSSKSS PPPSPLYKVF LRRLLSSVSQ

250 260 270 280 290 300
TPHETFTHAV ACVIAISSHT PAPLESLRQL YSQTSQGDKK PPPWVHPEYL RYYVLVHDED

310 320 330 340 350 360
NDDIAQSTAL FDQMKRHFGL HCHLLRLRSN QCVLTDDDST IFPTPEWLSP VEDLISMGKQ

370 380 390 400 410 420
ESLIDVEAEP SYLFESDVTA IKSFVRELVA QSVIPHMENR VALWNDQVAS RRRGLSGRFM

430 440 450 460 470 480
SISKRWAGFG SGSRSSGSPF GGSSSGNYDS YQGFYQPDSP EAILRKMADY SFMLRDWKLA

490 500 510 520 530 540
ASTYDLLRTD FSNDKAWLYH AGAHEMCAVA TLLNPLSSTS KSRLESIEQL LETACYSYLT

550 560 570 580 590 600
RCSDPQNTLR TVILGAELLK SRGGIAAESA ARWSTRVLDM GLLGSIGRLL LFERVSACYA

610 620 630 640 650 660
SKIATHGTGW GTRRRKAGMW SLFAAEGWLK QGQARLASSA MEEADRQYSD TVDDGTFPLP

670 680 690 700 710 720
EMQQVVDDLR LAIKVGCLEV RGMNGEGVET PTEVGPEETR ENLDYRGHGH RKSLMGGTNP

730 740
LEGIPTAPLR PLSPAEAAEP NDDFE


References and documentation are available.

Number of amino acids: 745 Molecular weight: 81783.71 Theoretical pI: 5.73
Amino acid composition: 
Ala (A) 54 7.2% Arg (R) 55 7.4% Asn (N) 12 1.6% Asp (D) 50 6.7% Cys (C) 9 1.2% Gln (Q) 27 3.6% Glu (E) 44 5.9% Gly (G) 55 7.4% His (H) 17 2.3% Ile (I) 28 3.8% Leu (L) 76 10.2% Lys (K) 25 3.4% Met (M) 14 1.9% Phe (F) 25 3.4% Pro (P) 49 6.6% Ser (S) 97 13.0% Thr (T) 39 5.2% Trp (W) 12 1.6% Tyr (Y) 18 2.4% Val (V) 39 5.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 94 Total number of positively charged residues (Arg + Lys): 80 Atomic composition: Carbon C 3584 Hydrogen H 5636 Nitrogen N 1020 Oxygen O 1127 Sulfur S 23 Formula: C3584H5636N1020O1127S23 Total number of atoms: 11390 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 93320 Abs 0.1% (=1 g/l) 1.141, assuming all pairs of Cys residues form cystines Ext. coefficient 92820 Abs 0.1% (=1 g/l) 1.135, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.34 This classifies the protein as unstable. Aliphatic index: 76.87 Grand average of hydropathicity (GRAVY): -0.415