ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSVKDQEVM LLISDRLLQG GKYNFKNIFR KDDRDFKTRK VIIVLVICLI FIITDLFIIR 

        70         80         90        100        110        120 
SHLHQISSRN QDTNSISALL NKQGVTFVKG MSSLKYKIFA FAQLNTNGSL QFESAISKQK 

       130        140        150        160        170        180 
FLNLNRKSKH INNNVNRILS IGGTNYSEKL SIMLQDLKKT RRFIMSIIRF LKDNELDGVE 

       190        200        210        220        230        240 
LLWNRNTEET LYCELLQHLK MGLEKQEKQY SISLRVPQTG IGKWHIGCEL EDQENADSIN 

       250        260        270        280        290        300 
LISMAEYENQ LFGSGGVIRI SEAFNTAWEM KYHACNSNQS SKFNLVIPTI EQTEQIDMQY 

       310        320        330        340        350 
VWNPEKKEIQ RFNSSTKTEY TKLQMGGVSI WSRDMDYHNN IQLDSYFFER ICSQELGK 

References and documentation are available.

Number of amino acids: 358

Molecular weight: 41651.79

Theoretical pI: 8.88

Amino acid composition: 
Ala (A)   9	  2.5%
Arg (R)  17	  4.7%
Asn (N)  28	  7.8%
Asp (D)  16	  4.5%
Cys (C)   5	  1.4%
Gln (Q)  23	  6.4%
Glu (E)  24	  6.7%
Gly (G)  18	  5.0%
His (H)   7	  2.0%
Ile (I)  35	  9.8%
Leu (L)  36	 10.1%
Lys (K)  29	  8.1%
Met (M)  11	  3.1%
Phe (F)  18	  5.0%
Pro (P)   3	  0.8%
Ser (S)  32	  8.9%
Thr (T)  17	  4.7%
Trp (W)   5	  1.4%
Tyr (Y)  11	  3.1%
Val (V)  14	  3.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 40
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1853
Hydrogen    H	      2944
Nitrogen    N	       508
Oxygen      O	       550
Sulfur      S	        16

Formula: C1853H2944N508O550S16
Total number of atoms: 5871

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    44140
Abs 0.1% (=1 g/l)   1.060, assuming all pairs of Cys residues form cystines


Ext. coefficient    43890
Abs 0.1% (=1 g/l)   1.054, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.98
This classifies the protein as unstable.



Aliphatic index: 91.20

Grand average of hydropathicity (GRAVY): -0.407