ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTSWRDKSAK VQVKESELPS SIPAQTGLTF NIWYNKWSQG FAGNTRFVSP FALQPQLHSG 

        70         80         90        100        110        120 
KTRGDNDGQL FFCLFFAKGM CCLGPKCEYL HHIPDEEDIG KLALRTEVLD CFGREKFADY 

       130        140        150        160        170        180 
REDMGGIGSF RKKNKTLYVG GIDGALNSKH LKPAQIESRI RFVFSRLGDI DRIRYVESKN 

       190        200        210        220        230        240 
CGFVKFKYQA NAEFAKEAMS NQTLLLPSDK EWDDRREGTG LLVKWANEDP DPAAQKRLQE 

       250        260        270        280        290        300 
ELKLESLNMM VHLINNNTNS AGTEVNNKNN ERLDRTFPEA SVDNVKKRLL PLDNGMESDD 

       310        320        330 
FIEKLKKVKK NISRENISSK PSVGKLGGPL LDYLSSDED 

References and documentation are available.

Number of amino acids: 339

Molecular weight: 38430.56

Theoretical pI: 8.09

Amino acid composition: 
Ala (A)  18	  5.3%
Arg (R)  19	  5.6%
Asn (N)  23	  6.8%
Asp (D)  24	  7.1%
Cys (C)   6	  1.8%
Gln (Q)  11	  3.2%
Glu (E)  25	  7.4%
Gly (G)  25	  7.4%
His (H)   5	  1.5%
Ile (I)  14	  4.1%
Leu (L)  34	 10.0%
Lys (K)  32	  9.4%
Met (M)   7	  2.1%
Phe (F)  18	  5.3%
Pro (P)  14	  4.1%
Ser (S)  25	  7.4%
Thr (T)  12	  3.5%
Trp (W)   5	  1.5%
Tyr (Y)   7	  2.1%
Val (V)  15	  4.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 49
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      1697
Hydrogen    H	      2673
Nitrogen    N	       477
Oxygen      O	       516
Sulfur      S	        13

Formula: C1697H2673N477O516S13
Total number of atoms: 5376

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    38305
Abs 0.1% (=1 g/l)   0.997, assuming all pairs of Cys residues form cystines


Ext. coefficient    37930
Abs 0.1% (=1 g/l)   0.987, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.96
This classifies the protein as stable.



Aliphatic index: 73.36

Grand average of hydropathicity (GRAVY): -0.663