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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTTAVSPPPP QEQQLVHASQ TSRVSPKTVE SALNGLINWR SDKSKTEKPQ LLEEDELVYL

70 80 90 100 110 120
FVTLKKIPQK TRTNAYRIPL PHPLINPTVD SPEICLIIDD RPKSGLTKDD AMKKIKSENI

130 140 150 160 170 180
PITKVIKLSK LKSDYKAFEA KRKLCDSYDM FFTDRRIIPL LPRVIGKKFF TSKKIPVALD

190 200 210 220 230 240
LKHRNWKHQI EKACGSAMFF IRTGTCSVIK VGKLSMDICE ITENVMATLN GLVEFLPNKW

250 260 270 280 290 300
TYVRSLHLKL SESLALPIYQ SVPDLKLKID AFGSGKSVVQ EEKEGEVEEV VAVDGGEKSV

310 320 330 340 350 360
TGKGKKKKGR IHEVRYMDSN VAEVLDEDEI GGDEDNNEIV ESEEKKMKKR KKEVSEVAES

370 380 390 400 410 420
EKPMKKAAKG KLKPDVEKPM KKAAKGKSKP DVEKPMQKAA VKGKVKPDVV KLEKSKDGLK

430 440
AKKTTMVAKD ESGGGLKPKR KSVLRK


References and documentation are available.

Number of amino acids: 446 Molecular weight: 49970.45 Theoretical pI: 9.57
Amino acid composition: 
Ala (A) 24 5.4% Arg (R) 17 3.8% Asn (N) 12 2.7% Asp (D) 26 5.8% Cys (C) 5 1.1% Gln (Q) 10 2.2% Glu (E) 38 8.5% Gly (G) 24 5.4% His (H) 6 1.3% Ile (I) 25 5.6% Leu (L) 36 8.1% Lys (K) 74 16.6% Met (M) 12 2.7% Phe (F) 10 2.2% Pro (P) 27 6.1% Ser (S) 32 7.2% Thr (T) 21 4.7% Trp (W) 3 0.7% Tyr (Y) 7 1.6% Val (V) 37 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 64 Total number of positively charged residues (Arg + Lys): 91 Atomic composition: Carbon C 2221 Hydrogen H 3692 Nitrogen N 608 Oxygen O 657 Sulfur S 17 Formula: C2221H3692N608O657S17 Total number of atoms: 7195 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 27180 Abs 0.1% (=1 g/l) 0.544, assuming all pairs of Cys residues form cystines Ext. coefficient 26930 Abs 0.1% (=1 g/l) 0.539, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.75 This classifies the protein as stable. Aliphatic index: 82.78 Grand average of hydropathicity (GRAVY): -0.626