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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTTKYIFVTG GVVSSLGKGI TAASLGRLLK NRGMKVTIQK FDPYINVDPG TMSPYQHGEV

70 80 90 100 110 120
FVTDDGAETD LDLGHYERFI DINLNKNSNV TTGKIYSSVL KKERRGDYLG GTVQVIPHVT

130 140 150 160 170 180
NEIKERVFRA GRETNADVVI TEIGGTVGDI ESLPFLEAIR QIKSDIGVDN VMYIHCTLIP

190 200 210 220 230 240
YLAAAGEMKS KPTQHSVKEL RSLGIQPNVI VVRTEKPVPE EMKEKIALFC DIRKDSVIEA

250 260 270 280 290 300
RDADTLYEVP LDLQAQNLDE IVCDHLNLSC QEADMTEWKS LVEKVKNLSG LVKIALVGKY

310 320 330 340 350 360
VALPDAYLSV AEALRHAGYA FDADINIKWV DSEDVTAENV AEQLQGVDGI LVPGGFGDRG

370 380 390 400 410 420
IEGKIEAIRY AREQKIPFLG ICLGMQLASI EFARNVLGLE GAHSAEINPD TPHPIIDLLP

430 440 450 460 470 480
EQKDVEDMGG TLRLGLYPCK LKNGTLAQSA YNDQVIYERH RHRYEFNNQY REQMEAKGFM

490 500 510 520 530
FSGTSPDGRL VEIVELGDHP FFIASQFHPE FVSRPTRPQP LFREFIQASL RK


References and documentation are available.

Number of amino acids: 532 Molecular weight: 59254.60 Theoretical pI: 5.34
Amino acid composition: 
Ala (A) 35 6.6% Arg (R) 28 5.3% Asn (N) 21 3.9% Asp (D) 34 6.4% Cys (C) 6 1.1% Gln (Q) 21 3.9% Glu (E) 42 7.9% Gly (G) 43 8.1% His (H) 13 2.4% Ile (I) 40 7.5% Leu (L) 47 8.8% Lys (K) 31 5.8% Met (M) 11 2.1% Phe (F) 20 3.8% Pro (P) 25 4.7% Ser (S) 26 4.9% Thr (T) 26 4.9% Trp (W) 2 0.4% Tyr (Y) 18 3.4% Val (V) 43 8.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 76 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 2639 Hydrogen H 4185 Nitrogen N 717 Oxygen O 797 Sulfur S 17 Formula: C2639H4185N717O797S17 Total number of atoms: 8355 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 38195 Abs 0.1% (=1 g/l) 0.645, assuming all pairs of Cys residues form cystines Ext. coefficient 37820 Abs 0.1% (=1 g/l) 0.638, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.03 This classifies the protein as stable. Aliphatic index: 93.80 Grand average of hydropathicity (GRAVY): -0.242