ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTTNNDFYFA LLRISILQLL KAQGFDRARP SLVDVMTDLY AKFLSLLASE VSSIAQARCD 

        70         80         90        100        110        120 
QDDTIALQDI TLALENLGIV KPTNVLDVYD ENSELSSSRG MEKFKDWCIY STQLTDARIT 

       130        140        150        160        170        180 
ALPTVELLQS EEKESDPLSA IPDYLNQLLQ NKGAKQKLET KNRKTELIED LINNNGLDDW 

       190        200        210        220        230        240 
IKLVIARQRI NMIERASKKE SQNVPALPHI AGYKSSILSR HHHTTITNED RMPSAMTPRD 

       250        260        270        280        290        300 
EDALTEIQEN PFVTSKLPIM RKENRLENIT LSFEDEELES LGEVEGPNQK SQENNNEESF 

       310        320        330        340        350 
KENNKSLTES PHGDDRDISM FQFDSNVDTK WAEQEDMDST FQRRTSLDYG GYF 

References and documentation are available.

Number of amino acids: 353

Molecular weight: 40295.97

Theoretical pI: 4.66

Amino acid composition: 
Ala (A)  20	  5.7%
Arg (R)  18	  5.1%
Asn (N)  24	  6.8%
Asp (D)  29	  8.2%
Cys (C)   2	  0.6%
Gln (Q)  18	  5.1%
Glu (E)  33	  9.3%
Gly (G)  11	  3.1%
His (H)   5	  1.4%
Ile (I)  22	  6.2%
Leu (L)  39	 11.0%
Lys (K)  21	  5.9%
Met (M)   9	  2.5%
Phe (F)  12	  3.4%
Pro (P)  13	  3.7%
Ser (S)  31	  8.8%
Thr (T)  23	  6.5%
Trp (W)   3	  0.8%
Tyr (Y)   8	  2.3%
Val (V)  12	  3.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 62
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1753
Hydrogen    H	      2789
Nitrogen    N	       483
Oxygen      O	       582
Sulfur      S	        11

Formula: C1753H2789N483O582S11
Total number of atoms: 5618

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    28545
Abs 0.1% (=1 g/l)   0.708, assuming all pairs of Cys residues form cystines


Ext. coefficient    28420
Abs 0.1% (=1 g/l)   0.705, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.60
This classifies the protein as unstable.



Aliphatic index: 82.92

Grand average of hydropathicity (GRAVY): -0.659