ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTVPFKIPIS DLDYCLEQLL DHKPPKILPP ETIQQLCHTL KTELLQTPNI ISLQSPISVV 

        70         80         90        100        110        120 
GDIHGQYHDL LEIFQIGGSP PQTNYLFLGD YVDRGYYSVE TISLLLVLKL RYPERVFLIR 

       130        140        150        160        170        180 
GNHESRTITT NYGFYTEVLN KYQGSADVWT FITDLFDYLP LGATIDGKIF ACHGGLSPSC 

       190        200        210        220        230        240 
QQLDQIRAVD RFREIPHDGI MADLVWSDPD VAISDFKLSP RGAGYLFGND VIDKFCQDNN 

       250        260        270        280        290        300 
LVQMIRAHQL CNEGYTSYWK GKCLTVWSAP NYCYRCGNKA SVLEILHSNY DSKDPTNGSD 

       310        320        330        340        350        360 
GEISSINGEF IGVNTSFESF GDDDDDYNDY RNRFNNSSRL HKQQGVLPGQ FFNVFEASKE 

       370        380        390        400        410 
NDEDTLQGKS VNGINFDDEL STSDDTSGSG GNNNKGDFFA AFFQERPKRQ QVEYFL 

References and documentation are available.

Number of amino acids: 416

Molecular weight: 47040.42

Theoretical pI: 4.72

Amino acid composition: 
Ala (A)  13	  3.1%
Arg (R)  16	  3.8%
Asn (N)  26	  6.2%
Asp (D)  37	  8.9%
Cys (C)   9	  2.2%
Gln (Q)  22	  5.3%
Glu (E)  20	  4.8%
Gly (G)  33	  7.9%
His (H)  10	  2.4%
Ile (I)  27	  6.5%
Leu (L)  39	  9.4%
Lys (K)  18	  4.3%
Met (M)   3	  0.7%
Phe (F)  25	  6.0%
Pro (P)  20	  4.8%
Ser (S)  32	  7.7%
Thr (T)  21	  5.0%
Trp (W)   4	  1.0%
Tyr (Y)  20	  4.8%
Val (V)  21	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 57
Total number of positively charged residues (Arg + Lys): 34

Atomic composition:

Carbon      C	      2103
Hydrogen    H	      3180
Nitrogen    N	       554
Oxygen      O	       652
Sulfur      S	        12

Formula: C2103H3180N554O652S12
Total number of atoms: 6501

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    52300
Abs 0.1% (=1 g/l)   1.112, assuming all pairs of Cys residues form cystines


Ext. coefficient    51800
Abs 0.1% (=1 g/l)   1.101, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.21
This classifies the protein as stable.



Aliphatic index: 79.64

Grand average of hydropathicity (GRAVY): -0.426