ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTVSKIPIWL DCDPGHDDAI AILLGCFHPA FNLLGISTCF GNAPPENTDY NARSLLTAMG 

        70         80         90        100        110        120 
KAQAIPVYKG AQRPWKREPH YAPDIHGISG LDGTSLLPKP TFEARTDKTY IEAIEEAILA 

       130        140        150        160        170        180 
NNGEISFVST GALTTLATVF RCKPYLKKSV KYISIMGGGL HGLGNCNPNL SAEFNVWIDP 

       190        200        210        220        230        240 
DAANYIFRDP DVKDKCIVVP LNLTHKAIAT YKVNEMIYNE KNNSKLRELF LELFQFFAHT 

       250        260        270        280        290        300 
YKDMQGFESG PPIHDPVALM PLLEFYGWDP SSAVGFRYKR MDISCIDDVF NENSGKIIIE 

       310        320        330        340 
KEYPNDSDVG TIIGLDLNIQ YFWDQIFEAL NRADKMSTIG 

References and documentation are available.

Number of amino acids: 340

Molecular weight: 37960.38

Theoretical pI: 5.22

Amino acid composition: 
Ala (A)  26	  7.6%
Arg (R)  10	  2.9%
Asn (N)  21	  6.2%
Asp (D)  24	  7.1%
Cys (C)   7	  2.1%
Gln (Q)   6	  1.8%
Glu (E)  18	  5.3%
Gly (G)  24	  7.1%
His (H)   8	  2.4%
Ile (I)  30	  8.8%
Leu (L)  29	  8.5%
Lys (K)  21	  6.2%
Met (M)   8	  2.4%
Phe (F)  18	  5.3%
Pro (P)  22	  6.5%
Ser (S)  18	  5.3%
Thr (T)  17	  5.0%
Trp (W)   5	  1.5%
Tyr (Y)  14	  4.1%
Val (V)  14	  4.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1720
Hydrogen    H	      2635
Nitrogen    N	       439
Oxygen      O	       501
Sulfur      S	        15

Formula: C1720H2635N439O501S15
Total number of atoms: 5310

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    48735
Abs 0.1% (=1 g/l)   1.284, assuming all pairs of Cys residues form cystines


Ext. coefficient    48360
Abs 0.1% (=1 g/l)   1.274, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.98
This classifies the protein as stable.



Aliphatic index: 87.26

Grand average of hydropathicity (GRAVY): -0.159