ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MTVYTASVTA PVNIATLKYW GKRDTKLNLP TNSSISVTLS QDDLRTLTSA ATAPEFERDT 

        70         80         90        100        110        120 
LWLNGEPHSI DNERTQNCLR DLRQLRKEME SKDASLPTLS QWKLHIVSEN NFPTAAGLAS 

       130        140        150        160        170        180 
SAAGFAALVS AIAKLYQLPQ STSEISRIAR KGSGSACRSL FGGYVAWEMG KAEDGHDSMA 

       190        200        210        220        230        240 
VQIADSSDWP QMKACVLVVS DIKKDVSSTQ GMQLTVATSE LFKERIEHVV PKRFEVMRKA 

       250        260        270        280        290        300 
IVEKDFATFA KETMMDSNSF HATCLDSFPP IFYMNDTSKR IISWCHTINQ FYGETIVAYT 

       310        320        330        340        350        360 
FDAGPNAVLY YLAENESKLF AFIYKLFGSV PGWDKKFTTE QLEAFNHQFE SSNFTARELD 

       370        380        390 
LELQKDVARV ILTQVGSGPQ ETNESLIDAK TGLPKE 

References and documentation are available.

Number of amino acids: 396

Molecular weight: 44115.91

Theoretical pI: 5.52

Amino acid composition: 
Ala (A)  37	  9.3%
Arg (R)  16	  4.0%
Asn (N)  16	  4.0%
Asp (D)  22	  5.6%
Cys (C)   5	  1.3%
Gln (Q)  16	  4.0%
Glu (E)  27	  6.8%
Gly (G)  18	  4.5%
His (H)   7	  1.8%
Ile (I)  19	  4.8%
Leu (L)  34	  8.6%
Lys (K)  25	  6.3%
Met (M)  10	  2.5%
Phe (F)  20	  5.1%
Pro (P)  15	  3.8%
Ser (S)  38	  9.6%
Thr (T)  31	  7.8%
Trp (W)   7	  1.8%
Tyr (Y)  10	  2.5%
Val (V)  23	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 49
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1960
Hydrogen    H	      3062
Nitrogen    N	       522
Oxygen      O	       606
Sulfur      S	        15

Formula: C1960H3062N522O606S15
Total number of atoms: 6165

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    53650
Abs 0.1% (=1 g/l)   1.216, assuming all pairs of Cys residues form cystines


Ext. coefficient    53400
Abs 0.1% (=1 g/l)   1.210, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.84
This classifies the protein as stable.



Aliphatic index: 78.38

Grand average of hydropathicity (GRAVY): -0.284